Table 1.
Descriptive characteristics of baseline factors in study participants (n = 383) 1.
| Control Group (n = 147) |
CHC Group (n = 236) |
p Value | |
|---|---|---|---|
| Age (years) | 54.82 ± 9.96 | 55.11 ± 8.70 | 0.7705 |
| Gender (F/M) | 71/76 | 120/116 | 0.6276 |
| BMI | 25.09 ± 3.80 | 25.33 ± 3.57 | 0.5337 |
| Total viral load [log10 (IU/mL) #] | N/A | 5.62 ± 0.84 | N/A |
| HCV genotype (type1/non-type1/missing) |
N/A | (131/100/5) | N/A |
| HCC (−/+) % | N/A | (94.9/5.1) | N/A |
| LC (−/+) % | N/A | (86/14) | N/A |
| Cr | 0.98 ± 0.18 | 0.83 ± 0.25 | < 0.0001 * |
| AST (IU/L) | 24.62 ± 9.13 | 90.13 ± 52.90 | < 0.0001 * |
| ALT (IU/L) | 26.48 ± 18.23 | 122.48 ± 69.00 | < 0.0001 * |
| GGT (IU/L) | 33.08 ± 23.50 | 68.46 ± 65.51 | < 0.0001 * |
| WBC | 6370.88 ± 1699.14 | 5430.42 ± 1623.39 | < 0.0001 * |
| PLT(×103/µL) | 252.85± 66.63 | 152.42 ± 61.06 | < 0.0001 * |
| Hemoglobin (g/dL) | 14.42 ± 1.44 | 14.02 ± 1.46 | 0.0085 * |
| TG (mg/dL) | 133.42 ± 99.02 | 98.87 ± 56.52 | 0.0002 * |
| CHLO (mg/dL) | 213.61 ± 39.74 | 169.11 ± 35.53 | < 0.0001 * |
| HDL-C (mg/dL) | 55.54 ± 14.26 | 45.47 ± 14.87 | < 0.0001 * |
| LDL-C (mg/dL) | 123.20 ± 33.33 | 99.54 ± 31.78 | < 0.0001 * |
| AC_sugar (mg/dL) | 92.26 ± 20.49 | 103.71 ± 32.25 | < 0.0001 * |
| HbA1c (%) | 5.88 ± 0.78 | 5.92 ± 1.07 | 0.7101 |
1 BMI, body mass index; HCC, hepatocellular carcinoma; LC, liver cirrhosis; Cr, creatinine; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γGT, gamma-glutamyl transferase; WBC, white blood cell count; PLT, platelet count; TG, triglyceride; CHLO, cholesterol; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; AC_Sugar, fasting plasma glucose; HbA1c, hemoglobin A1c. All values are expressed as the mean ± standard deviation (SD). The p value was calculated for the continuous variables using the Student’s t-test or Mann–Whitney test, and the χ2 test was used for the categorical variables, with α = 0.05. * = p < 0.05. # The HCV virus loads were determined by log-transformation.