Table 3.
Correlation between circulating expression of let-7 family members and various clinical parameters (n = 236) 1.
Age | AST | ALT | PLT | HCV RNA | ||
---|---|---|---|---|---|---|
Cluster1 | let7a | −0.0986 | −0.1898 * | −0.0772 | 0.2433 * | 0.1118 |
let7d | −0.0846 | −0.1757 | −0.0747 | 0.2209 * | 0.0829 | |
let7e | −0.1431 | −0.1504 | −0.0546 | 0.2113 * | 0.1211 | |
let7g | −0.1495 | −0.2038 * | −0.1041 | 0.1911 * | 0.1386 | |
Cluster2 | let7b | −0.0172 | −0.0746 | −0.0106 | 0.1384 | 0.1118 |
let7i | −0.1141 | −0.126 | −0.0153 | 0.1365 | 0.0848 | |
Cluster3 | let7c | −0.0456 | −0.1298 | −0.0448 | 0.0473 | 0.0753 |
let7f | −0.045 | −0.1576 | −0.0499 | 0.0728 | 0.1442 | |
miR98 | −0.0195 | −0.0915 | −0.0373 | 0.0046 | 0.062 |
1 Data represents correlation between miRNA expression and the values of each clinical parameter, as reported in Table 1. Correlation was determined using Pearson’s test. AST, aspartate aminotransferase; ALT, alanine aminotransferase; PLT, platelet count; HCV, hepatitis C viral load. * = p < 0.05 following the Bonferroni correction (α = 0.0056).