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. 2020 Jul 17;21(14):5067. doi: 10.3390/ijms21145067

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of chronic ouabain (Oua) and lipopolysaccharide (LPS) administration on the barrier properties of rat jejunum and colon. Rats were intraperitoneally injected with ouabain (1 µg/kg) for 4 days. (a) Transepithelial resistance (TER) dynamics. (b) TER values measured at 30 min of registration. (c) Apparent permeability measured as the paracellular flux of sodium fluorescein. N—the number of rats (in parentheses is the number of fragments). The number of symbols corresponds to the number of fragments. One-way ANOVA with Dunnett correction: * p < 0.05 and ** p < 0.01—LPS-treated group compared with the corresponding control (vehicle treated group). # p < 0.05—Oua + LPS compared with LPS-treated group. p = 0.09 in (c) corresponds to comparison with the control.