Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 21;21(14):5166. doi: 10.3390/ijms21145166

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Regulation of LPS-induced cytokine secretion by LfP analogs. U937-derived macrophages were treated with FKECHLA, FKECH, EKF or YKE peptides (1–1000 µM) for 24 h and then treated with LPS (100 ng/mL, 24 h). Culture media was collected and its cytokine content was determined by standard ELISA for TNF-α (A), IL-6 (B), IL-10 (C) or TGF-β (D). Results are representative from three experiments and presented as mean ± SD with biological and analytical duplicates for each treatment. * indicate p < 0.05 compared to treatment with LPS alone. All treatments were statistically different from untreated cells, except cells treated by LPS and 1 or 10 μM FKECH in (A) (ANOVA).

Regulation of LPS-induced cytokine secretion by LfP analogs. U937-derived macrophages were treated with FKECHLA, FKECH, EKF or YKE peptides (1–1000 µM) for 24 h and then treated with LPS (100 ng/mL, 24 h). Culture media was collected and its cytokine content was determined by standard ELISA for TNF-α (A), IL-6 (B), IL-10 (C) or TGF-β (D). Results are representative from three experiments and presented as mean ± SD with biological and analytical duplicates for each treatment. * indicate p < 0.05 compared to treatment with LPS alone. All treatments were statistically different from untreated cells, except cells treated by LPS and 1 or 10 μM FKECH in (A) (ANOVA).