TABLE 2.
Diagnostic criteria for disseminated intravascular coagulation from three different organizations
| International Society on Thrombosis and Hemostasis | Japanese Association of Acute Medicine | Japanese Ministry of Health and Welfare | |
|---|---|---|---|
| Underlying disease | 0 points, but patient must have an underlying disorder known to be associated with DIC | 1 point | 0 points, but patient must have an underlying disorder known to be associated with DIC |
| Clinical symptoms | 0 points |
Bleeding: 1 point Organ failure: 1 point |
SIRS score ≥ 3: 1 point |
| Platelet count (×103/μL) |
>100—0 points <100 but >50—1 point <50—2 points |
>120—0 points <120 but >80—1 point <80 but >50—2 points <50—3 points |
<120 but >80 or >30% drop—1 point <80 or >50% drop—3 points |
| Fibrin‐related marker |
Elevated fibrin monomers/degradation products: No increase: 0 Moderate increase: 2 Strong increase: 3 |
Fibrin degradation products μg/mL >10 but <20—1 point >20 but <40—2 points >40—3 points |
Fibrin degradation products μg/mL >10 but <25—1 point >25—3 points |
| Prothrombin time (PT) |
Prothrombin time: <3 seconds—0 >3 but <6—1 >6 seconds—2 |
PT ratio: >1.25 but <1.67—1 point >1.67—2 points |
PT ratio: >1.2—1 point |
| Fibrinogen (g/L) |
>1 g: 0 <1 g: 1 |
>1 but <1.5—1 point <1—2 points |
None |
| Total score to diagnose DIC | ≥5 | ≥7 points | ≥4 points |