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Direct Cross-Coupling of Pharmaceuticals
Conditions: Ar-X (1.0 equiv), Ar-B(OH)2 (2.0 equiv), K2CO3 (3.0 equiv), [Pd(IPr)(μ-Cl)Cl]2 (6) (y mol %), EtOH (0.50 M), 12 h. Isolated yields. aiPrOH. bK2CO3 (5 equiv). ct-BuOH. See Transparent Methods for details.
