TABLE 1.
Clinical and laboratory parameters for patients A‐C with cell counts prior to receipt of systemic corticosteroids
| Patient | A | B | C |
|---|---|---|---|
| Age (years) | 9 | 8 | 6 |
| Sex | F | M | M |
| Ethnicity | African American | African American | Not reported |
| Clinical features | Fever, hypotension, coronary artery dilation, LV dysfunction, hypoxemia, rash, conjunctivitis | Fever, hypotension, abdominal pain, emesis, rash | Fever, hypotension, LV dysfunction, hypoxemia, abdominal pain, AKI, conjunctivitis |
| Hematologic parameters | |||
| WBC (1 × 103/μL) | 12.9 | 7.42 | 7.65 |
| Neutrophil/band (%) | 87.7 | 87 | 93 |
| Immature granulocytes (%) | 0.6 | 1.7 | 2.6 |
| Lymphocyte (%) | 7.4 | 8 | 2 |
| ANC (1 × 103/μL) | 11.3 | 6.46 | 7.11 |
| ALC (1 × 103/μL) | 0.95 | 0.58 | 0.15 |
| ANC/ALC ratio | 11.9 | 11.1 | 47.4 |
| Left shift | Present | Present | Present |
| Inflammatory markers (peak) | |||
| CRP a (mg/dL) | 17.4 | 35.2 | 25.8 |
| Ferritin (ng/mL) | 1500 | 1471 | 1203 |
| D‐dimer b (μg/mL) | 10.9 | 5.9 | 8.2 |
| SARS‐CoV‐2 RT‐PCR | Negative | Negative | Positive |
| SARS‐CoV‐2 serologies | Positive | Positive | Positive |
Note. Peak inflammatory markers are shown here along with results of SARS‐CoV‐2 RT‐PCR and serologic testing.
Abbreviations: AKI, acute kidney injury; ALC, absolute lymphocyte count; ANC, absolute neutrophil count; ANC/ALC ratio, absolute neutrophil count to absolute lymphocyte count ratio; CRP, C‐reactive protein; LV, left ventricular; RT‐PCR, reverse transcription polymerase chain reaction; WBC, white blood cell count.
a
Normal range < 0.5 mg/dL.
b
Normal range < 0.5 μg/mL.