Table 1.
Extract | Acetylcholinesterase Inhibition | HMGR * Inhibition | Inhibition of Cholesterol Permeation (%) | ||
---|---|---|---|---|---|
1000 µg/mL | IC50 (µg/mL) | 10 µg/mL | IC50 (µg/mL) | ||
Ocean samples | 89.96% ± 0.54 a | 210.86 ± 22.11 a | 27.74% ± 1.60 a | - | - |
Ocean samples–SPE fraction | - | 14.97 ± 0.13 b | 86.41% ± 3.20 b | 4.16 ± 0.11 | 45.3 ± 4.4 |
Tagus samples | 4.199% ± 0.36 b | - | 1.07% ± 0.65 c | - | - |
Tagus samples–SPE fraction | 60.44% ± 1.21c | 849.80 ± 10.24 c | 52.95% ± 3.17 d | - | - |
* 3-hidroxi-3-methyl-glutaril-CoA reductase; Superscript letters (a–d) correspond to values in the same column that can be considered statistically different (p = 0.05).