Table 1.
COVID‐19 patients with positive HIT EIA at a large academic medical center
Patient | Age | Sex | Race | Heparin exposure | Indication | Thrombosis? | Platelet nadir (109/L) | 4Ts | EIA OD | SRA result | HIT diagnosis? | Outcome | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Score | Risk | ||||||||||||
1 | 50 | M | AA |
UFH SQ UFH IV |
Prophylaxis ECMO |
No | 49 | 5 | Intermediate | 0.626 | Negative | No | Death |
2 | 79 | F | W | LMWH | Prophylaxis | No | 155 | 3 | Low | 1.881 | Negative | No | Discharge |
3 | 58 | F | AA | LMWH | Prophylaxis | PTE | 305 | 3 | Low | 0.505 | Negative | No | Death |
4 | 61 | F | AA | UFH IV | CRRT | No | 37 | 4 | Intermediate | 0.950 | Positive | Yes | Pending |
5 | 38 | M | W |
LMWH UFH IV |
Prophylaxis ECMO |
No | 39 | 3 | Low | 0.828 | Negative | No | Pending |
6 | 71 | F | AA |
UFH SQ UFH IV |
Prophylaxis CRRT |
Stroke | 70 | 6 | High | 0.465 | Negative | No | Death |
7 | 46 | M | AA | LMWH | Prophylaxis | DVT | 59 | 5 | Intermediate | 0.828 | Negative | No | Pending |
Abbreviations: AA, African American; CRRT, continuous renal replacement therapy; DVT, deep vein thrombosis; ECMO, extracorporeal membrane oxygenation; EIA, enzyme immunoassay; F, female; LMWH, low‐molecular‐weight heparin; M, male; OD, optical density; PTE, pulmonary thromboembolism; SRA, serotonin release assay; UFH, unfractionated heparin; W, White.