Table 2.

Alignment statistics stratified by premalignant lesion status

Factor	Overall (n=82)	No Lesions (n=25)	Lesions (n=50)	P*
Total Alignments	90M (17M)	90M (15M)	91M (19M)	0.78
Unique Alignments	83M (16M)	83M (14M)	84M (17M)	0.76
Properly Paired Alignments	66M (12M)	66M (11M)	67M (14M)	0.75
Genebody 80/20 Ratio	1.3 (0.2)	1.3 (0.1)	1.3 (0.2)	0.84
Mean GC Content	47.8 (3.4)	47.4 (2.9)	48.2 (3.7)	0.34

Data are means (SD) for continuous variables and proportions with percentages for dichotomous variables. Reads are expressed in millions denoted by M. P* values are for the comparison of subjects with and without premalignant lesions. Two sample t-tests were used for continuous variables; Fisher’s exact test was used for factors.