FIGURE 1.

Overview of the mechanisms of action of the repurposed drugs undergoing clinical trials for the treatment of COVID‐19 that are reviewed here. Compounds in red represent those that are viral entry inhibitors, compounds in green represent disruptors of cellular viral processing, compounds in blue are modulators of the hyperinflammatory phase of infection, and compounds in yellow stimulate host immunomodulatory and antiviral activity. ISRE, IFN‐stimulated response element; P, phosphate; RdRp, RNA‐dependent RNA polymerase; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2