Table 3.

Top-ten genes up- (↑) and downregulated (↓) by AFB1 exposure. For each DEG (AFB1 vs PCB126), Ensembl gene ID, log₂ fold change (logFC), and False Discovery Rate (FDR) are provided as reported in edgeR output. The Ensembl gene description and acronym are also provided.

Ensembl Gene ID	logFC	FDR	Gene Description	Gene Acronym	Pattern of Expression
ENSBTAG00000017425	6.38	1.74 × 10−17	Gap junction protein beta 2	GJB2	↑
ENSBTAG00000003329	3.40	1.98 × 10−16	Follistatin	FST	↑
ENSBTAG00000011316	4.09	7.33 × 10−16	Zinc finger CCCH-type containing 12A	ZC3H12A	↑
ENSBTAG00000004256	2.91	1.06 × 10−15	Ornithine decarboxylase 1	ODC1	↑
ENSBTAG00000005039	2.65	1.24 × 10−15	A-Raf proto-oncogene, serine/threonine kinase	ARAF	↑
ENSBTAG00000019716	7.54	1.24 × 10−15	C-X-C motif chemokine ligand 8	CXCL8	↑
ENSBTAG00000014324	2.97	1.50 × 10−15	ANTXR cell adhesion molecule 2	ANTXR2	↑
ENSBTAG00000011358	3.74	1.63 × 10−15	Immediate early response 3	IER3	↑
ENSBTAG00000000507	3.62	2.80 × 10−15	Nuclear receptor subfamily 4 group A member 1	NR4A1	↑
ENSBTAG00000001864	5.47	3.68 × 10−15	Nuclear receptor subfamily 4 group A member 3	NR4A3	↑
ENSBTAG00000007665	−3.35	1.98 × 10−16	Natriuretic peptide receptor 3	NPR3	↓
ENSBTAG00000013848	−4.20	1.98 × 10−16	Adhesion G protein-coupled receptor D1	ADGRD1	↓
ENSBTAG00000023907	−3.52	1.98 × 10−16	Collagen type XVIII alpha 1 chain	COL18A1	↓
ENSBTAG00000004231	−5.70	1.98 × 10−16	Glycoprotein M6A	GPM6A	↓
ENSBTAG00000007494	−3.34	1.98 × 10−16	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	SMARCA2	↓
ENSBTAG00000013391	−3.66	2.19 × 10−16	ANKH inorganic pyrophosphate transport regulator	ANKH	↓
ENSBTAG00000013472	−3.83	2.24 × 10−16	Collagen type I alpha 2 chain	COL1A2	↓
ENSBTAG00000034693	−5.91	2.79 × 10−16	Synaptotagmin 1	SYT1	↓
ENSBTAG00000001405	−3.78	2.99 × 10−16	Glucuronic acid epimerase	GLCE	↓
ENSBTAG00000017448	−4.08	3.46 × 10−16	EGF containing fibulin extracellular matrix protein 1	EFEMP1	↓