Table 4.

Gene expression (↑, upregulation; ↓, downregulation) of CYP isoforms after AFB1 treatment. For each DEG (AFB1 vs PCB126), Ensembl gene ID, log₂ fold change (logFC), and False Discovery Rate (FDR) are provided as reported in edgeR output. The Ensembl gene description and acronym are also provided.

Ensembl Gene ID	logFC	FDR	Gene Description	Gene Acronym	Pattern of Expression
ENSBTAG00000012212	5.16	1.3 × 10−14	cytochrome P450, family 26, subfamily B, polypeptide	CYP26B1	↑
ENSBTAG00000052665	4.01	9.7 × 10−14	cytochrome P450, subfamily IIIA, polypeptide 4	CYP3A4 CYP3A28	↑
ENSBTAG00000016906	5.43	4.3 × 10−13	cytochrome P450, family 27, subfamily B, polypeptide 1	CYP27B1	↑
ENSBTAG00000010531	−1.87	4.4 × 10−8	cytochrome P450, family 1, subfamily B, polypeptide 1	CYP1B1	↓
ENSBTAG00000012972	−1.39	1.3 × 10−6	cytochrome P450, family 2, subfamily U, polypeptide 1	CYP2U1	↓
ENSBTAG00000014890	−5.61	1.8 × 10−6	cytochrome P450, family 19, subfamily A, polypeptide 1	CYP19A1	↓
ENSBTAG00000003632	−1.91	3.0 × 10−6	cytochrome P450, family 39, subfamily A, polypeptide 1	CYP39A1	↓
ENSBTAG00000039319	−2.09	7.3 × 10−6	cytochrome P450, family 4, subfamily F, polypeptide 2	CYP4F2	↓
ENSBTAG00000011976	−5.65	1.0 × 10−5	cytochrome P450, family 4, subfamily B, polypeptide 1	CYP4B1	↓
ENSBTAG00000053766	−3.24	7.7 × 10−5	cytochrome P450 2J2-like	CYP2J2L	↓
ENSBTAG00000003871	−3.31	0.00031	cytochrome P450 subfamily 2B	CYP2B6	↓
ENSBTAG00000001021	−1.28	0.00064	cytochrome P450 family 1 subfamily A member 1	CYP1A1	↓