Table 5.
Concentration (mM) of lactic acid and short-chain fatty acids (SCFA) infant faecal samples after non-fructosylated α-GOS and β-GOS fermentation.
| SCFA (mM) | Control | α-GOS | β-GOS | p-Values | Pooled SEM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bs | 6 h | 24 h | Bs | 6 h | 24 h | Bs | 6 h | 24 h | T | Prebiotics | T * Prebiotics | Bs | ||
| Acetate | 14.669 | 21.640 a | 18.908 a | 10.808 | 44.356 b | 45.752 b | 16.587 | 33.463 b | 40.743 b | 0.671 | 0.001 | 0.677 | 0.084 | 2.313 |
| Propionate | 3.163 | 6.491 | 6.116 | 2.915 | 9.130 | 8.522 | 3.971 | 8.196 | 10.072 | 0.839 | 0276 | 0.746 | 0.060 | 0.729 |
| Butyrate | 3.408 | 6.664 | 4.900 | 6.727 | 6.970 | 6.772 | 7.512 | 7.719 | 8.112 | 0.728 | 0714 | 0.831 | 0.044 | 0.746 |
| Iso-butyrate | 0.307 | 0.649 | 0.764 | 0.253 | 0.700 | 0.791 | 0.339 | 0.582 | 0.624 | 0.540 | 0.605 | 0.975 | 0.412 | 0.067 |
| Valerate | 1.174 | 4.228 | 4.788 | 1.139 | 2.216 | 0.607 | 1.197 | 2.102 | 2.249 | 0.779 | 0.059 | 0.678 | 0.000 | 0.531 |
| Iso-valerate | 0.317 | 0.635 | 0.827 | 0.303 | 0.775 | 0.719 | 0.236 | 0.602 | 0.657 | 0.682 | 0.897 | 0.806 | 0.052 | 0.077 |
| Formate | 0.611 | 2.400 a | 2.447 a | 0.523 | 3.651 b | 8.954 b | 0.785 | 4.042 a, b | 3.115 a, b | 0.258 | 0.046 | 0.117 | 0.390 | 0.643 |
| Succinate | 0.265 | 1.022 | 1.022 | 0.428 | 1.065 | 0.975 | 0.354 | 1.018 | 0.969 | 0.899 | 0.998 | 0.995 | 0.967 | 0.182 |
| Lactate | 0.248 | 0.782 a | 0.500 a | 0.211 | 3.908 b | 1.554 b | 0.343 | 1.353 a, b | 0.559 a, b | 0.028 | 0.009 | 0.225 | 0.015 | 0.250 |
Outcomes were analyzed using a linear mixed model: repeat measure. A Bonferroni method was used for adjustments for major effects (time of treatment and type of GOS). a, b Mean value with different letters means that differences among treatments was significantly different at p-value < 0.05. Unadjusted mean values n = 8. Bs: Baseline like covariate. * Interaction among major effects.