Table 3.
Raw data means and median for PN subtypes 1–3
| Group | PN1 | PN2 | PN3 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| # | Property | Mean | SEM | Median | MAD | Mean | SEM | Median | MAD | Mean | SEM | Median | MAD |
| 1 | RMP (mV) | –73.5 | 0.51 | –73.9 | 2.01 | –74.5 | 0.34 | –74.8 | 1.59 | –71.2 | 0.40 | –71.5 | 1.92 |
| 2 | Rm (MΩ) | 247 | 15.6 | 248 | 55.4 | 173 | 11.4 | 151 | 38.4 | 222 | 10.7 | 219 | 43.0 |
| 3 | ct | 117 | 8.23 | 100 | 40.0 | 216 | 13.1 | 220 | 60.0 | 125 | 8.43 | 120 | 40.0 |
| 4 | ADP probability | 0.17 | 0.07 | 0.00 | 0.00 | 0.26 | 0.07 | 0.00 | 0.00 | 0.89 | 0.05 | 1.00 | 0.00 |
| 5 | Mean ADP value (mV) | 0.08 | 0.05 | 0.00 | 0.00 | 0.24 | 0.08 | 0.00 | 0.00 | 1.54 | 0.15 | 1.46 | 0.70 |
| 6 | Max initial adaptation change(Hz/pA) | 0.47 | 0.02 | 0.44 | 0.08 | 1.25 | 0.10 | 0.99 | 0.35 | 2.99 | 0.13 | 3.18 | 0.48 |
| 7 | Max adaptation change relative to ct | 2.01 | 0.10 | 1.95 | 0.45 | 1.35 | 0.04 | 1.28 | 0.09 | 1.30 | 0.03 | 1.25 | 0.10 |
| 8 | Initial adaptation change (Hz/pA) (2) | 0.47 | 0.02 | 0.44 | 0.08 | 1.16 | 0.09 | 0.91 | 0.27 | 2.58 | 0.14 | 2.74 | 0.67 |
| 9 | Max adaptation change relativeto ct (2) | 2.01 | 0.10 | 1.95 | 0.45 | 1.37 | 0.04 | 1.29 | 0.08 | 1.34 | 0.03 | 1.33 | 0.13 |
| 10 | AHP amplitude (mV) | –14.9 | 0.50 | –14.8 | 2.17 | –14.6 | 0.51 | –14.5 | 1.99 | –10.1 | 0.38 | –10.2 | 1.59 |
| 11 | AHP latency (ms) | 12.3 | 1.51 | 9.22 | 2.77 | 13.1 | 1.99 | 6.57 | 2.27 | 64.4 | 10.3 | 56.5 | 51.8 |
| 12 | Max AP rise (mV/ms) | 225 | 6.77 | 222 | 25.0 | 183 | 5.35 | 191 | 30.5 | 216 | 5.80 | 215 | 22.7 |
| 13 | Max AP decay (mV/ms) | –39.7 | 1.23 | –39.1 | 4.69 | –38.2 | 0.93 | –38.3 | 3.91 | –44.2 | 0.80 | –43.8 | 3.13 |
| 14 | AP half-width (ms) | 1.95 | 0.05 | 1.94 | 0.16 | 1.81 | 0.04 | 1.76 | 0.14 | 1.57 | 0.03 | 1.57 | 0.13 |
| 15 | AP threshold (mV) | –35.6 | 0.53 | –36.1 | 1.98 | –32.4 | 0.47 | –32.1 | 1.95 | –34.8 | 0.27 | –34.8 | 1.11 |
| 16 | AP amplitude (mV) | 81.4 | 0.76 | 81.6 | 2.82 | 71.8 | 0.73 | 71.5 | 3.08 | 77.1 | 0.46 | 77.2 | 1.68 |
| 17 | 2xct: number of AP | 20.1 | 0.63 | 20.0 | 2.00 | 15.0 | 0.69 | 14.5 | 2.50 | 17.8 | 0.64 | 17.5 | 2.50 |
| 18 | 2xct: latency to first AP | 17.5 | 0.72 | 17.8 | 3.02 | 15.3 | 0.70 | 15.2 | 2.58 | 21.5 | 0.82 | 21.3 | 3.44 |
| 19 | 2xct: AHP amplitude (mV) | –11.1 | 0.56 | –11.3 | 2.59 | –6.48 | 0.56 | –6.15 | 2.06 | –2.98 | 0.40 | –2.84 | 1.40 |
| 20 | 2xct: AHP amplitude latency (ms) | 4.41 | 0.12 | 4.34 | 0.32 | 4.12 | 0.08 | 4.06 | 0.32 | 3.37 | 0.06 | 3.39 | 0.28 |
| 21 | 2xct: max AP rise (mV/ms) | 227 | 7.41 | 224 | 24.2 | 200 | 7.32 | 190 | 35.9 | 210 | 6.29 | 205 | 30.5 |
| 22 | 2xct: max AP decay (mV/ms) | –45.7 | 1.43 | –44.5 | 5.47 | –43.6 | 1.07 | –43.0 | 4.69 | –48.5 | 0.99 | –48.4 | 4.69 |
| 23 | 2xct: AP half-width (ms) | 1.63 | 0.03 | 1.64 | 0.09 | 1.78 | 0.04 | 1.77 | 0.17 | 1.48 | 0.03 | 1.46 | 0.11 |
| 24 | 2xct: AP threshold (mV) | –37.3 | 0.56 | –37.7 | 2.47 | –35.7 | 0.74 | –36.7 | 2.96 | –36.8 | 0.26 | –36.7 | 1.40 |
| 25 | 2xct: AP amplitude (mV) | 78.8 | 0.80 | 78.7 | 2.54 | 72.6 | 0.75 | 73.9 | 2.64 | 75.5 | 0.50 | 75.9 | 2.16 |
| 26 | 2xct: 1st/2nd AP ratio | 1.17 | 0.02 | 1.14 | 0.03 | 1.30 | 0.02 | 1.30 | 0.09 | 1.44 | 0.02 | 1.41 | 0.10 |
| 27 | 2xct: 2nd/3rd AP ratio | 1.05 | 0.01 | 1.05 | 0.02 | 0.99 | 0.01 | 0.99 | 0.04 | 0.92 | 0.01 | 0.93 | 0.07 |
| 28 | 2xct: 1st /last AP ratio | 1.60 | 0.05 | 1.56 | 0.20 | 1.38 | 0.03 | 1.32 | 0.12 | 1.18 | 0.01 | 1.16 | 0.07 |
| 29 | 2xct: initial instant frequency | 35.5 | 1.15 | 34.7 | 3.25 | 71.4 | 2.72 | 72.7 | 11.2 | 101 | 2.87 | 100 | 13.0 |
| 30 | 2xct: max adaptation (Hz) | 17.5 | 1.20 | 18.2 | 3.50 | 58.7 | 2.66 | 59.1 | 13.2 | 87.0 | 2.81 | 86.0 | 11.9 |
| 31 | 2xct: ISI ratio | 0.52 | 0.03 | 0.50 | 0.07 | 0.17 | 0.01 | 0.17 | 0.06 | 0.15 | 0.01 | 0.14 | 0.03 |
| 32 | 2xct: average initial burst interva (ms) first 3 AP | 33.8 | 1.00 | 33.8 | 3.89 | 21.2 | 1.08 | 19.7 | 3.59 | 18.9 | 1.28 | 16.0 | 4.54 |
| 33 | 2xct: SD of average initial burstinterval first 3 AP | 6.64 | 0.69 | 5.88 | 1.87 | 8.65 | 0.85 | 7.73 | 2.61 | 12.3 | 1.56 | 7.95 | 4.07 |
| 34 | 2xct: change of initial interspikeinterval (ms) | 9.29 | 1.00 | 8.32 | 2.64 | 12.2 | 1.20 | 10.9 | 3.69 | 17.4 | 2.21 | 11.2 | 5.76 |
| 35 | 2xct: initial change of instantfrequency | –8.65 | 0.85 | –8.74 | 2.24 | –30.5 | 1.73 | –30.6 | 5.09 | –54.3 | 2.27 | –56.0 | 12.4 |
| 36 | 2xct: Cv2:all | 0.08 | 0.01 | 0.07 | 0.01 | 0.24 | 0.02 | 0.21 | 0.09 | 0.17 | 0.01 | 0.16 | 0.04 |
| 37 | 2xct: Cv2-1st AP | 0.06 | 0.00 | 0.06 | 0.01 | 0.22 | 0.02 | 0.18 | 0.10 | 0.12 | 0.01 | 0.11 | 0.03 |
| 38 | 2xct: Cv2-1st/2nd AP | 0.06 | 0.00 | 0.05 | 0.01 | 0.21 | 0.02 | 0.15 | 0.09 | 0.09 | 0.01 | 0.08 | 0.02 |
Means are indicated with their SEM, while medians are indicated with their median absolute deviation (MAD).