Table 5.
Statistical comparison of all PN subtypes (including the outlier VIP-IN)
Group | Kruskal–Wallis | Dunn’s multiple comparison test | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
# | Property | p value | H value | η2 | PN1vsPN2 | PN1vsPN3 | PN1vsPN4 | PN1vsPN5 | PN1vsVIP | PN2vsPN3 | PN2vsPN4 | PN2vsPN5 | PN2vsVIP | PN3vsPN4 | PN3vsPN5 | PN3vsVIP | PN4vsPN5 | PN4vsVIP | PN5vsVIP |
1 | RMP (mV) | 3.0E-13 | 67.8 | 0.37 | 1.0E+00 | 3.1E-02 | 7.5E-04 | 7.6E-06 | 6.2E-01 | 1.6E-05 | 6.2E-08 | 1.6E-09 | 2.7E-01 | 1.0E+00 | 9.1E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
2 | Rm (MΩ) | 4.6E-11 | 57.2 | 0.31 | 4.2E-03 | 1.0E+00 | 1.0E+00 | 1.5E-03 | 1.0E+00 | 5.1E-02 | 2.1E-03 | 8.9E-12 | 2.4E-01 | 1.0E+00 | 8.9E-06 | 1.0E+00 | 5.0E-04 | 1.0E+00 | 1.0E+00 |
3 | ct | 2.1E-15 | 78.0 | 0.43 | 1.3E-04 | 1.0E+00 | 1.0E+00 | 1.7E-04 | 1.0E+00 | 8.4E-05 | 2.1E-05 | 0.0E+00 | 1.4E-01 | 1.0E+00 | 9.9E-06 | 1.0E+00 | 8.0E-05 | 1.0E+00 | 1.0E+00 |
4 | ADP probability | 1.1E-16 | 83.8 | 0.47 | 1.0E+00 | 6.3E-09 | 5.5E-10 | 6.5E-05 | 1.0E+00 | 4.1E-08 | 3.3E-09 | 4.6E-04 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
5 | ADP mean | 3.3E-16 | 82.1 | 0.46 | 1.0E+00 | 1.9E-10 | 3.3E-08 | 1.8E-04 | 1.0E+00 | 9.0E-10 | 2.1E-07 | 1.2E-03 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
6 | Max initial adaptationchange (Hz/pA) | 0.0E+00 | 121 | 0.69 | 6.0E-05 | 0.0E+00 | 6.6E-10 | 2.4E-03 | 3.4E-02 | 1.5E-09 | 3.8E-01 | 1.0E+00 | 7.1E-01 | 6.7E-04 | 1.4E-05 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 8.0E-01 |
7 | Max adaptationchange relativeto ct | 1.9E-15 | 78.3 | 0.44 | 8.6E-08 | 1.5E-09 | 8.9E-03 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.8E-01 | 1.1E-07 | 4.7E-01 | 2.3E-02 | 3.9E-09 | 3.3E-01 | 2.6E-03 | 1.0E+00 | 1.0E+00 |
8 | Initial adaptationchange (Hz/pA) (2) | 0.0E+00 | 106 | 0.6 | 2.3E-05 | 0.0E+00 | 2.9E-09 | 2.0E-04 | 3.5E-02 | 2.9E-07 | 1.0E+00 | 1.0E+00 | 8.3E-01 | 3.2E-03 | 2.2E-03 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
9 | Max adaptationchange relativeto ct (2) | 0.0E+00 | 88.7 | 0.5 | 2.5E-08 | 3.9E-09 | 8.3E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 8.5E-03 | 3.5E-10 | 3.8E-01 | 2.8E-03 | 6.3E-11 | 3.3E-01 | 1.3E-03 | 1.0E+00 | 1.0E+00 |
10 | AHP amplitude (mV) | 8.3E-12 | 60.8 | 0.33 | 1.0E+00 | 2.8E-08 | 9.2E-05 | 2.4E-01 | 5.1E-01 | 1.5E-08 | 1.2E-04 | 4.4E-01 | 6.4E-01 | 1.0E+00 | 1.8E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
11 | AHP latency (ms) | 3.7E-04 | 22.8 | 0.11 | 1.0E+00 | 1.0E+00 | 5.4E-02 | 1.0E+00 | 1.0E+00 | 1.5E-01 | 2.2E-04 | 7.4E-01 | 1.0E+00 | 9.7E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 7.4E-01 | 1.0E+00 |
12 | Max AP rise (mV/ms) | 2.8E-10 | 53.4 | 0.29 | 5.3E-04 | 1.0E+00 | 2.7E-07 | 1.6E-04 | 1.0E+00 | 3.9E-03 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.7E-06 | 1.1E-03 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
13 | Max AP decay (mV/ms) | 3.1E-12 | 62.9 | 0.34 | 1.0E+00 | 5.2E-02 | 1.2E-02 | 2.1E-02 | 1.0E+00 | 6.6E-04 | 7.4E-02 | 1.0E-01 | 1.0E+00 | 1.1E-10 | 6.6E-08 | 1.0E+00 | 1.0E+00 | 5.1E-01 | 4.0E-01 |
14 | AP half-width (ms) | 8.4E-13 | 65.6 | 0.36 | 3.0E-01 | 4.1E-08 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.2E-03 | 3.4E-02 | 3.7E-01 | 1.0E+00 | 5.1E-11 | 1.7E-06 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
15 | AP threshold (mV) | 1.9E-06 | 34.5 | 0.18 | 7.2E-05 | 1.0E+00 | 3.5E-03 | 1.4E-02 | 1.0E+00 | 2.1E-03 | 1.0E+00 | 1.0E+00 | 4.9E-01 | 7.0E-02 | 1.6E-01 | 1.0E+00 | 1.0E+00 | 7.9E-01 | 6.8E-01 |
16 | AP amplitude (mV) | 1.1E-13 | 69.8 | 0.39 | 6.6E-13 | 2.2E-02 | 1.2E-07 | 2.9E-06 | 1.0E+00 | 1.6E-05 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 4.7E-02 | 6.4E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
17 | 2xct: number of AP | 1.1E-13 | 66.9 | 0.37 | 1.6E-04 | 4.8E-01 | 7.1E-09 | 4.1E-10 | 2.6E-01 | 1.7E-01 | 5.9E-01 | 1.4E-02 | 1.0E+00 | 7.5E-05 | 1.9E-06 | 8.9E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
18 | 2xct: latencyto first AP | 0.0E+00 | 87.7 | 0.49 | 1.0E+00 | 1.6E-01 | 6.1E-05 | 5.5E-09 | 1.0E+00 | 1.3E-04 | 5.2E-10 | 4.7E-14 | 1.0E+00 | 2.9E-01 | 9.6E-05 | 1.0E+00 | 1.3E-01 | 1.0E+00 | 6.7E-01 |
19 | 2xct: AHP amplitude (mV) | 1.1E-16 | 85.0 | 0.48 | 4.3E-04 | 4.0E-14 | 2.6E-10 | 1.0E+00 | 8.2E-01 | 8.2E-04 | 6.6E-02 | 2.9E-01 | 1.0E+00 | 1.0E+00 | 6.7E-07 | 1.0E+00 | 8.4E-05 | 1.0E+00 | 1.0E+00 |
20 | 2xct: AHP amplitudelatency (ms) | 1.1E-13 | 69.8 | 0.39 | 9.5E-01 | 3.1E-10 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.8E-06 | 1.0E+00 | 3.2E-01 | 1.0E+00 | 5.5E-08 | 2.4E-09 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
21 | 2xct: max AP rise(mV/ms) | 5.3E-10 | 52.0 | 0.28 | 1.4E-01 | 1.0E+00 | 1.0E-08 | 1.7E-04 | 1.0E+00 | 1.0E+00 | 1.2E-03 | 2.1E-01 | 1.0E+00 | 3.3E-06 | 1.0E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
22 | 2xct: max APdecay (mV/ms) | 3.3E-12 | 62.8 | 0.34 | 1.0E+00 | 1.0E+00 | 4.9E-05 | 5.2E-03 | 1.0E+00 | 4.7E-02 | 7.8E-04 | 4.5E-02 | 1.0E+00 | 4.2E-11 | 2.1E-06 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
23 | 2xct: AP half-width (ms) | 8.9E-11 | 55.8 | 0.3 | 2.4E-01 | 6.6E-02 | 1.6E-02 | 1.0E+00 | 1.0E+00 | 1.0E-07 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 3.5E-10 | 8.1E-04 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
24 | 2xct: AP threshold (mV) | 8.0E-05 | 26.3 | 0.13 | 1.0E+00 | 1.0E+00 | 5.7E-03 | 9.0E-03 | 1.0E+00 | 1.0E+00 | 2.6E-01 | 2.2E-01 | 1.0E+00 | 1.3E-02 | 2.1E-02 | 1.0E+00 | 1.0E+00 | 5.5E-01 | 4.0E-01 |
25 | 2xct: AP amplitude (mV) | 8.3E-09 | 46.2 | 0.25 | 7.8E-06 | 1.9E-01 | 9.5E-08 | 1.8E-04 | 1.0E+00 | 6.9E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 2.8E-03 | 1.5E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
26 | 2xct: 1st/2nd AP ratio | 4.4E-16 | 81.4 | 0.46 | 3.6E-03 | 1.6E-11 | 6.2E-09 | 1.0E+00 | 1.0E+00 | 2.7E-03 | 6.0E-02 | 2.5E-02 | 1.0E+00 | 1.0E+00 | 2.1E-08 | 9.2E-01 | 1.3E-06 | 1.0E+00 | 1.0E+00 |
27 | 2xct: 2nd/3rdAP ratio | 0.0E+00 | 95.3 | 0.54 | 6.9E-03 | 8.6E-10 | 0.0E+00 | 7.7E-05 | 1.0E+00 | 1.4E-02 | 7.8E-09 | 9.6E-01 | 1.0E+00 | 3.6E-02 | 1.0E+00 | 1.0E+00 | 3.8E-02 | 1.0E+00 | 1.0E+00 |
28 | 2xct: 1st /lastAP ratio | 0.0E+00 | 90.2 | 0.51 | 5.4E-01 | 6.7E-11 | 2.4E-10 | 2.5E-10 | 1.0E+00 | 2.0E-06 | 5.0E-06 | 1.4E-06 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
29 | 2xct: initial instantfrequency | 0.0E+00 | 128 | 0.73 | 7.6E-07 | 0.0E+00 | 1.8E-05 | 1.0E+00 | 1.0E+00 | 1.4E-04 | 1.0E+00 | 3.0E-06 | 1.0E+00 | 1.4E-05 | 0.0E+00 | 8.3E-02 | 3.8E-05 | 1.0E+00 | 1.0E+00 |
30 | 2xct: maxadaptation (Hz) | 0.0E+00 | 127 | 0.73 | 6.9E-08 | 0.0E+00 | 2.1E-07 | 1.0E+00 | 1.0E+00 | 2.7E-04 | 1.0E+00 | 4.3E-05 | 9.5E-01 | 2.4E-04 | 1.3E-14 | 8.4E-02 | 8.1E-05 | 1.0E+00 | 1.0E+00 |
31 | 2xct: ISI ratio | 0.0E+00 | 97.1 | 0.55 | 2.0E-11 | 0.0E+00 | 4.3E-13 | 6.1E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 1.7E-03 | 1.0E+00 | 1.0E+00 | 1.9E-05 | 1.0E+00 | 2.1E-04 | 1.0E+00 | 1.0E+00 |
32 | 2xct: average initial burstinterval (ms) first 3 AP | 0.0E+00 | 92.1 | 0.52 | 1.2E-05 | 2.8E-08 | 1.0E+00 | 3.4E-01 | 1.0E+00 | 1.0E+00 | 3.5E-04 | 6.0E-10 | 3.7E-01 | 1.1E-06 | 8.7E-13 | 1.9E-01 | 1.9E-02 | 1.0E+00 | 1.0E+00 |
33 | 2xct: SD of averageinitial burst intervalfirst 3 AP | 1.9E-14 | 73.5 | 0.41 | 1.0E+00 | 2.6E-01 | 1.2E-09 | 1.1E-07 | 2.2E-01 | 1.0E+00 | 1.6E-07 | 7.6E-06 | 4.8E-01 | 5.9E-05 | 5.2E-04 | 8.7E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
34 | 2xct: change of initialinterspike interval (ms) | 1.9E-14 | 73.5 | 0.41 | 1.0E+00 | 2.6E-01 | 1.2E-09 | 1.1E-07 | 2.2E-01 | 1.0E+00 | 1.6E-07 | 7.6E-06 | 4.8E-01 | 5.9E-05 | 5.2E-04 | 8.7E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
35 | 2xct: initial changeof instant frequency | 0.0E+00 | 123 | 0.7 | 1.7E-05 | 0.0E+00 | 3.2E-13 | 1.0E+00 | 1.0E+00 | 8.6E-06 | 2.7E-02 | 2.5E-02 | 1.0E+00 | 1.0E+00 | 3.4E-11 | 6.7E-01 | 4.6E-07 | 1.0E+00 | 1.0E+00 |
36 | 2xct: Cv2:all | 5.6E-16 | 80.8 | 0.45 | 1.8E-11 | 5.8E-06 | 8.0E-14 | 3.3E-09 | 3.8E-02 | 3.2E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 2.3E-02 | 2.0E-01 | 9.7E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
37 | 2xct: Cv2-1st AP | 9.1E-15 | 75.1 | 0.42 | 9.2E-13 | 3.0E-05 | 1.3E-10 | 1.7E-08 | 4.6E-02 | 2.9E-02 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 2.3E-01 | 2.0E-01 | 9.3E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |
38 | 2xct: Cv2-1st/2nd AP | 1.3E-13 | 69.6 | 0.38 | 5.1E-10 | 1.3E-01 | 5.4E-08 | 1.7E-07 | 9.7E-02 | 1.1E-04 | 1.0E+00 | 1.0E+00 | 1.0E+00 | 3.2E-03 | 1.6E-03 | 5.0E-01 | 1.0E+00 | 1.0E+00 | 1.0E+00 |