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. 2021 Jan 1;184(1):141–150. doi: 10.1111/bjd.19415

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© 2021 British Association of Dermatologists

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Light microscopic findings and myxovirus resistance protein A (MXA) expression in idiopathic perniosis. (a) In each case there is a superficial and deep angiocentric lymphocytic infiltrate [haematoxylin and eosin (HE), original magnification × 100]. (b) There is a lymphocytic eccrine hidradenitis (HE, × 200). (c) The infiltrates surround and permeate capillaries and venules in the superficial and deep dermis. There are proplastic endothelial cell alterations and focal red cell extravasation without fibrin deposition (HE, × 200). (d) In all cases there is a striking expression of MXA in the epidermis, eccrine ducts and glands, inflammatory cells and endothelium (diaminobenzidine, × 200). Each scale bar is set at 125 microns.