Fig. 1.

MTHFR C677T allelic frequency (Y-axis) with respect to cumulative age (X- axis) in different patient age groups. The MTHFR C677T allelic frequency in all Helicobacter pylori-negative patients included in the study. The frequency of the TT genotype was significantly higher among patients aged ≤44 years than among patients over 44 years (41.18% vs. 18.92%; P = 0.039). The two horizontal lines represent the genotype frequencies in 128 patients in our study (TT = 21.88%, CT = 53.91%). b. The MTHFR C677T allelic frequency in patients aged 27–44 years. c. MTHFR C677T allelic frequency in Helicobacter pylori-negative patients aged 45–80 years