Table 4.
Expression of efflux pump genes in evolved, resistant P. aeruginosa, selected by levofloxacina
| Passage | mexA | mexC | mexE | mexX |
|---|---|---|---|---|
| 0. (0MIC) | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| 1. (1/2MIC) | 0.6700 | 2.6295 | 1.4200 | 1.3850 |
| 2. (1MIC) | 1.2310 | 8.6650 | 5.4625 | 2.2925 |
| 3. (2MIC) | 0.9325 | 16.2745 | 8.3645 | 1.2030 |
| 4. (4MIC) | 0.8605 | 152.1040 | 2.6225 | 3.0995 |
| 5. (8MIC) | 1.2310 | 52.7525 | 12.0805 | 1.3095 |
| 6. (16MIC) | 1.0385 | 57.6390 | 15.4695 | 2.0900 |
| 7. (32MIC) | 1.4255 | 145.8855 | 10.5065 | 4.6735 |
| 8. (64MIC) | 1.5140 | 74.2490 | 12.8310 | 7.5555 |
aRelative expression levels represent the median of the six lineages