Table II.
Top 10 up- and downregulated DEGs.
| A, Upregulated DEGs | |||
|---|---|---|---|
| Gene symbol | Description | Fold-change | P-value |
| BNIP3 | BCL2 interacting protein 3 | 5.58 | 0.001235 |
| EFEMP1 | EGF-containing fibulin-like extracellular matrix protein 1 | 3.73 | 0.006757 |
| GNB4 | G protein subunit β 4 | 3.65 | 0.001084 |
| NETO2 | Neuropilin and tolloid-like 2 | 3.55 | 0.000477 |
| LY75 | Lymphocyte antigen 75 | 3.34 | 0.010767 |
| TSHZ3 | Teashirt zinc finger homeobox 3 | 3.24 | 0.001838 |
| LIMS3 | LIM zinc finger domain-containing 3 | 3.19 | 0.0000414 |
| TMSB15B | Thymosin β 15B | 3.01 | 0.003074 |
| NAP1L5 | Nucleosome assembly protein 1-like 5 | 2.90 | 0.000186 |
| CLDN10 | Claudin 10 | 2.86 | 0.007955 |
| B, Downregulated DEGs | |||
| SPON1 | Spondin 1 | 0.22 | 0.0000353 |
| CDH11 | Cadherin 11 | 0.22 | 0.0173247 |
| SDPR | Caveolae-associated protein 2 | 0.31 | 0.0000935 |
| SOSTDC1 | Sclerostin domain-containing 1 | 0.31 | 0.0012579 |
| LUM | Lumican | 0.33 | 0.0286506 |
| IL1B | Interleukin 1 β | 0.35 | 0.0179449 |
| ESM1 | Endothelial cell specific molecule 1 | 0.36 | 0.0003328 |
| CCL20 | C-C motif chemokine ligand 20 | 0.36 | 0.0003672 |
| SULF2 | Sulfatase 2 | 0.36 | 0.0227548 |
| PDE4B | Phosphodiesterase 4B | 0.37 | 0.0005664 |
DEGs, differentially expressed genes.