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. 2020 Jul 15;20(4):5. doi: 10.3892/ol.2020.11866

Table V.

Hub genes associated with perineural invasion.

Gene Description Degree
AR Androgen receptor 32
MAPT Microtubule-associated protein τ 15
TEK TEK receptor tyrosine kinase 13
SNCA Synuclein α 12
UBE2E1 Ubiquitin-conjugating enzyme E2 E1 12
GLI1 GLI-Kruppel family member GLI1 12
FGFR1 Fibroblast growth factor receptor 1 11
ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 11
PRKG1 Protein kinase, cGMP-dependent, type I 11
CCR5 C-C motif chemokine receptor 5 10
GNB4 G protein subunit β 4 10
WWTR1 WW domain-containing transcription regulator 1 10
PGR Progesterone receptor 8
FGF2 Fibroblast growth factor 2 7
TNS1 Tensin 1 7
NPSR1 Neuropeptide S receptor 1 7
MITF Melanogenesis-associated transcription factor 6
FLT3 Fms-like tyrosine kinase 3 6
TGFB2 Transforming growth factor β 2 6