Table 1.
Patient characteristics and laboratory results
| ICU | Non‐ICU | P | |
|---|---|---|---|
| Patients, n | 48 | 30 | ‐ |
| Age, y | 62.8 ± 13.1 | 60.2 ± 14.6 | .39 |
| BMI, kg/m2 | 29 ± 5.5 | 26.2 ± 4.8 | .07 |
| SOFA score | 5.4 ± 3.1 | ‐ | ‐ |
| SAPS II score | 37.9 ± 13 | ‐ | ‐ |
| Fibrinogen, g/L (normal values = 2‐4) | 6.1 ± 1.9 | 5.6 ± 1.7 | .38 |
| FVIII, % (normal values = 50‐150) | 199 ± 65 | 160 ± 28 | .22 |
| Antithrombin, % (normal values = 80‐120) | 87 ± 28 | 106 ± 14 | .016 |
| D‐dimers, ng/mL (normal values < 500) | 3456 ± 2641 | 874 ± 539 | .0019 |
| Peak thrombin, nM (normal values = 350 ± 39) | 312 ± 127 | 391 ± 76 | .004 |
| ETP, nM/min (normal values = 1593 ± 206) | 1682 ± 610 | 1815 ± 357 | .31 |
| t‐PA, ng/mL (normal values = 2‐12) | 23.9 ± 14.5 | 14.4 ± 7.5 | <.0001 |
| PAI‐1, ng/mL (normal values = 4‐43) | 96.3 ± 35 | 76.8 ± 40 | .017 |
| TAFIa/i, ng/mL (normal values = 1.76‐28.9) | 60.2 ± 42.3 | 39.8 ± 23.8 | .016 |
| Alpha 2 antiplasmin, UI/dL (normal values = 80‐120) | 124.6 ± 15.8 | 128 ± 9.2 | .41 |
| Patients, n | 19 | 4 | ‐ |
| TEM‐tPA MCF, mm (normal values = 32 ± 10.4) | 62.3 ± 10 | 61.5 ± 6.5 | .69 |
| TEM‐tPA alpha angle, (normal values = 69 ± 5) | 81 ± 1.4 | 79 ± 2.3 | .065 |
| Ly30, % (normal values = 1.8 ± 3.2) | 63 ± 39 | 18 ± 35 | .022 |
BMI, body mass index; SAPS II, Simplified Acute Physiology Score; SOFA, sequential organ failure assessment.