Table 4.

Differences in Parafoveal (0.5–1.5 mm From the Foveal Center) and Perifoveal (1.5–3.0 mm From the Foveal Center) Retinal Layer Thicknesses Between the Participants With Aniridia (n = 26) and Normal Controls

		95% Confidence Interval				95% Confidence Interval
Retinal Layer	Mean Difference (µm)	Upper	Lower	P Value	Mean Difference (µm)	Upper	Lower	P Value
	Nasal Parafovea				Temporal Parafovea
Inner retinal layers (RNFL + GCL + IPL)	−9.77	−4.69	−14.85	<0.001	−3.29	2.33	−8.91	0.25
Inner nuclear layer	5.45	10.62	0.28	0.039	2.40	8.12	−3.33	0.41
Outer plexiform layer	4.63	9.80	−0.54	0.079	1.39	7.12	−4.33	0.63
Outer retinal layers (ONL + IS + OS + RPE)	−31.09	−26.09	−36.09	<0.001	−30.96	−25.43	−36.48	<0.001
Outer nuclear layer	−21.55	−18.52	−24.58	<0.001	−26.33	−22.02	−30.65	<0.001
	Nasal Perifovea				Temporal Perifovea
Inner retinal layers (RNFL + GCL + IPL)	−16.91	−11.23	−22.59	<0.001	−6.65	−2.46	−10.84	0.002
Inner nuclear layer	2.69	8.49	−3.10	0.36	−0.28	3.98	−4.55	0.90
Outer plexiform layer	4.82	10.62	−0.97	0.10	1.45	5.72	−2.81	0.50
Outer retinal layers (ONL + IS + OS + RPE)	−13.92	−8.33	−19.50	<0.001	−14.50	−10.31	−18.69	<0.001
Outer nuclear layer	−11.28	−8.42	−14.13	<0.001	−15.45	−12.08	−18.82	<0.001

Outer nuclear thickness could only be calculated for a subset of the aniridia patients (n = 19). IS, inner segment.