Table 4.
Differentially Expressed lncRNAs That Contained Sequences Similar to Genes or Proteins Related to POAG, Steroid Metabolism, Cell Adhesion, or Inflammation
| Gene Name | Gene Homology | Fold Change | P |
|---|---|---|---|
| POAG-related genes and proteins | |||
| NONHSAT106523.2:1153-1748 | Forkhead box C1 | 2256.23 | 4.54E-02 |
| NONHSAT148308.1:1169-1667 | Optineurin | 1147.99 | 4.80E-02 |
| NONHSAT193696.1:1-739 | TGF-β receptor 2 | –2.09 | 3.38E-02 |
| NONHSAT089825.2:124-841 | TGF-β receptor associated protein 1 | –8.22 | 1.55E-02 |
| Steroid metabolism | |||
| NONHSAT148979.1:0-1359 | 24-Dehydrocholesterol reductase | 2.03 | 9.74E-03 |
| NONHSAT169506.1:0-838 | Ergosterol biosynthesis 28 homolog | 2.78 | 1.56E-03 |
| NONHSAT213073.1:0-1897 | G protein-coupled estrogen receptor 1 | 5.23 | 2.64E-02 |
| NONHSAT195547.1:0-1485 | Oxysterol binding protein like 10 | 3.25 | 3.35E-02 |
| Cell adhesion | |||
| NONHSAT024227.2:247-402 | Neural cell adhesion molecule 1 | 204,369.47 | 3.02E-02 |
| NONHSAT200405.1:6-227 | Protocadherin 10 | 449,931.40 | 2.30E-02 |
| NONHSAT200404.1:2-362 | Protocadherin 10 | 39076.04 | 3.81E-02 |
| NONHSAT128959.2:135-645 | Protocadherin 10 | 6607.54 | 1.21E-02 |
| NONHSAT060854.2:68-438 | Protocadherin 10 | 5069.50 | 3.21E-02 |
| NONHSAT221848.1:287-1259 | Protocadherin related 15 | –7.03 | 3.76E-02 |
| Inflammation | |||
| NONHSAT021960.2:14-890 | Vascular endothelial growth factor B | 4054.53 | 2.00E-02 |
| NONHSAT182278.1:5-557 | Interleukin-1 receptor type 1 | –2.19 | 4.15E-02 |
| NONHSAT166437.1:6-363 | Interleukin-17D | –13.84 | 2.88E-02 |
| NONHSAT123398.2:8765-9729 | Nuclear factor-κB activating protein | 19,639.21 | 4.49E-02 |