Table 1.
Baseline Characteristics of the UM Patients and Tumor Samples Analyzed for Protein Expression
| Patients (n = 34) | |
|---|---|
| Sex | |
| Female | 16 (47.1%) |
| Male | 18 (52.9%) |
| Age in years, mean (SD) | 66.88 (11.6) |
| Tumor location | |
| Ciliary body | 2 (5.9%) |
| Choroid | 32 (94.1%) |
| Tumor size in mm, Mean (SD) | |
| Base 1 | 12.12 (4.1)* |
| Base 2 | 12.53 (4.6)* |
| Prominence | 7.58 (4.3)* |
| Tumor samples (n = 38) | |
| Sample acquisition | |
| Biopsy | 2 (5.3%) |
| Resection | 15 (39.5%) |
| Enucleation | 21 (55.3%) |
| Irradiation | |
| No | 18 (47.4%) |
| Yes | 20 (52.6%) |
| Prominent cell type | |
| Spindle | 5 (13.2%) |
| Mixed | 20 (52.6%) |
| Epithelioid | 13 (34.2%) |
| M3-positive cells | |
| Median | 30.0% |
| Min–Max | 8.8%–85.5% |
| Chromosome 3 index | |
| Median | 1.0 |
| Min–Max | 0.7–1.6 |
| M3 status | |
| Low | 13 (34.2%) |
| Intermediate | 9 (23.7%) |
| High | 16 (42.1%) |
| M3 status in non-irradiated tumors | 18 |
| Low | 4 (22.2%) |
| Intermediate | 3 (16.7%) |
| High | 11 (61.1%) |
| M3 status in irradiated tumors | 20 |
| Low | 9 (45.0%) |
| Intermediate | 6 (30.0%) |
| High | 5 (25.0%) |
SD, Standard deviation; M3, monosomy-3.
*
Data missing from one patient.