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Summary of the Gene Expression Profile in the RPE of WT and D2R KO Mice Between ZT 23 and ZT 1 Time Points
| WT | D2R KO | |
|---|---|---|
| Total transcripts (>1 RPKM) | 13,387 | 12,478 |
| Differentially expressed transcripts | 394 | 1054 |
| Upregulated | 247 | 651 |
| Downregulated | 147 | 403 |
| Fold change >2 | 183 | 854 |
| Fold change >=1.5 = <2 | 211 | 200 |
Although the total number of transcripts were not different between two genotypes, the number of DEGs were higher in the RPE of the D2R KO mouse than in WT.
