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. 2020 May 18;61(5):29. doi: 10.1167/iovs.61.5.29

Figure 1.

Figure 1.

TGF-β2 induces MMP-2 and MMP-9 expression in astrocytes cultured from human ONH. Levels of MMP-2 and MMP-9 in conditioned media were determined after incubation with TGF-β2 for 24 hours. Representative immunoblots (A) and quantitation of (B) MMP-2 and (C) MMP-9 expression are shown. TGF-β2 began to induce MMP-2 (∼72 kDa) at 1 ng/mL with maximal (twofold) induction at 5 ng/mL; it also maximally induced MMP-9 (∼92 kDa) by 2.4-fold at 5 ng/mL (*P < 0.05, †P < 0.01, ‡P < 0.001 vs. untreated; n = 4).