Table 3.
Univariate and Multivariate Analyses for Clinical Activity in Patients With TED
| Univariate Regression Model | Multivariate Regression Model | |||||
|---|---|---|---|---|---|---|
| Variable | OR | 95% CI | P | OR | 95% CI | P |
| IgG4 subtype | ||||||
| Definite | 8.73 | 2.74-27.8 | <0.001 | 6.83 | 2.07-22.6 | <0.001 |
| Probable | 6.11 | 2.38-15.7 | <0.001 | 5.83 | 2.19-15.5 | <0.001 |
| Possible | 2.25 | 0.72-7.04 | 0.165 | 1.60 | 0.48-5.30 | 0.445 |
| Female sex | 0.59 | 0.28-1.22 | 0.159 | |||
| Age at diagnosis, y | 1.04 | 1.00-1.07 | 0.024 | 1.03 | 0.99-1.07 | 0.086 |
| History of steroid use | 1.79 | 0.73-4.36 | 0.204 | 1.80 | 0.69-4.72 | 0.233 |
| Smoking history | 1.98 | 0.97-4.09 | 0.062 | 1.39 | 0.49-3.93 | 0.538 |
| I-131 therapy history | 0.48 | 0.18-1.34 | 0.161 | 0.63 | 0.21-1.90 | 0.414 |
TED, thyroid eye disease; IgG4, immunoglobulin G4; BCVA, best corrected visual acuity; OR, odds ratio; 95%CI, 95% confidence interval.
Significant P values are shown with bold characters.