Table 2.
Summary of Quantitative OCTA Features for Different DR Severity Levels
| Healthy Control n = 33 | No-DR n = 51 | Mild n = 41 | Mod/Severe | Proliferative | ||
|---|---|---|---|---|---|---|
| Outcomes | Area | Mean (± SD) | Mean (± SD) | Mean (± SD) | n = 37 Mean (± SD) | n = 30 Mean (± SD) | 
| PD of SCC | Parafovea | 0.50 (0.02) | 0.50 (0.02) | 0.48 (0.03) | 0.45 (0.04) | 0.42 (0.04) | 
| Temporal | 0.46 (0.02)* | 0.47 (0.03)* | 0.45 (0.04)* | 0.39 (0.05)* | 0.33 (0.07)* | |
| Nasal | 0.45 (0.04)* | 0.46 (0.03)* | 0.46 (0.04)* | 0.40 (0.05)* | 0.35 (0.08)* | |
| FD of SCC | Parafovea | 1.72 (0.01) | 1.72 (0.01) | 1.71 (0.01) | 1.70 (0.01) | 1.68 (0.02) | 
| Temporal | 1.70 (0.01)* | 1.71 (0.01)* | 1.70 (0.01)* | 1.68 (0.02)* | 1.65 (0.05)* | |
| Nasal | 1.71 (0.01)* | 1.70 (0.01)* | 1.70 (0.01)* | 1.68 (0.02)* | 1.66 (0.05)* | |
| PD of DCC | Parafovea | 0.49 (0.02) | 0.48 (0.03) | 0.47 (0.02) | 0.44 (0.04) | 0.43 (0.05) | 
| Temporal | 0.50 (0.02) | 0.48 (0.02) | 0.48 (0.03) | 0.41 (0.07) | 0.39 (0.09) | |
| Nasal | 0.50 (0.03) | 0.48 (0.03) | 0.47 (0.03) | 0.38 (0.08) | 0.39 (0.08) | 
Outcomes grouped according to retinal topography of 3 × 3 mm scanning areas. For the outcomes of the SCC, the area directly nasal to the optic disc was excluded because it showed significantly higher values than the supero- and inferonasal areas. Values in bold letters are significantly different to outcomes of DR severity one stage lower. Values marked with * are significantly different to values measured in the parafovea. The P values were adjusted according to the Tukey multiple testing method.
Mod = moderate.