Table 1. Alcohol-related measures in each target sample.

C, Continuous (linear regression model used); B, Binary (logistic regression model used)

Drinking measure		Definitions
Trait	Continuous/Binary	COGA Ascertained for AUD	ALSPAC Population-based	GS Population-based	UKB Population-based
Units per week (Mean, SD)	C	n/a	n/a	10.9 (12.8)	n/a
Alcohol use (N, %)	B	Ever drank once a month for 6 consecutive months or longer 6,163 (90.0%)	n/a	n/a	n/a
Maxdrinks (Median, SD)	C	Lifetime maximum drinks consumed in a single 24-hour period 14.0 (12.87)	Lifetime maximum drinks consumed in a single 24-hour period 15.0 (12.35)	n/a	n/a
Hazardous drinking (N, %)	B	n/a	AUDIT total score cutoff of 8+ at any age 3264 (66.2%)	n/a	n/a
AUDIT-C score (Mean, SD)	C	n/a	Sum of AUDIT items 1–3 Age 16 4.80 (2.59) Age 18 5.04 (2.26) Age 19 6.01 (2.50) Age 21 6.11 (2.43) Age 23 5.37 (2.31)	n/a	n/a
AUDIT-P score (Mean, SD)	C	n/a	Sum of AUDIT items 4–10 Age 16 2.37 (3.18) Age 18 2.48 (2.97) Age 19 2.38 (2.89) Age 21 3.16 (3.66) Age 23 2.30 (2.93)	n/a	n/a
DSM alcohol dependence symptom count (Mean, SD)	C	Sum of 11 lifetime criteria for diagnosis of DSM-5 AUD 3.57 (3.68)	Sum of 7 criteria for diagnosis of DSM-IV AUD; maximum observed across waves Age 18 0.35 (0.91) Age 21 0.72 (1.30) Age 23 0.43 (1.01)	n/a	n/a
DSM-IV alcohol dependence diagnosis (N, %)	B	Clustering of ≥3 of 7 DSM-IV criteria within 12 months 2,318 (33.8%)	Clustering of ≥3 of 7 DSM-IV criteria within 12 months at any wave of assessment (age 18, 21, or 23) 484 (11.2%)	n/a	n/a
ICD-9 and ICD-10 alcohol dependence diagnosis (N, %)	B	n/a	n/a	n/a	ICD-9 code of 303* or ICD-10 code of F10* 4,141 (1.68%)
CAGE scores (Range 0–4; Mean, SD)	C	n/a	n/a	0.603 (0.93)	n/a