Table 2.

Neonatal Characteristics and Morbidities of Infants in Relation to the Occurrence and Progression of ROP^*

	ROP Occurrence (Any Stage)			Severe ROP (Stage 3)			Vision-threatening ROP Requiring Treatment (Type 1)
Variables	Absent	Present	P Value	Absent	Present	P Value	Absent	Present	P Value
No. of infants	125	50		148	27		156	19
GA at birth (weeks)	29.5 ± 1.7	27.7 ± 2.0	<0.001	29.4 ± 1.8	27.0 ± 2.1	<0.001	29.4 ± 1.7	26.1 ± 1.7	<0.001
Birth weight (kg)	1.430 ± 0.324	1.118 ± 0.301	<0.001	1.403 ± 0.323	1.004 ± 0.277	<0.001	1.393 ± 0.321	0.913 ± 0.240	<0.001
Male	68 (54.4)	24 (48.0)	0.444	81 (54.7)	11 (40.7)	0.181	85 (54.5)	7 (36.8)	0.146
Apgar score <7
1 minute	90 (72.0)	40 (80.0)	0.274	107 (72.3)	23 (85.2)	0.159	113 (72.4)	17 (89.5)	0.163
5 minutes	36 (28.8)	25 (50.0)	0.008	48 (32.4)	13 (48.1)	0.115	51 (32.7)	10 (52.6)	0.085
Continuous positive airway pressure	102 (81.6)	42 (84.0)	0.707	122 (82.4)	22 (81.5)	1.000	127 (81.4)	17 (89.5)	0.533
Mechanical ventilation	59 (47.2)	37 (74.0)	0.001	75 (50.7)	21 (77.8)	0.009	79 (50.6)	17 (89.5)	0.001
Use of surfactant	39 (31.2)	29 (58.0)	0.001	52 (35.1)	16 (59.3)	0.018	57 (36.5)	11 (57.9)	0.071
EOS	13 (10.4)	13 (26.0)	0.009	18 (12.2)	8 (29.6)	0.034	19 (12.2)	7 (36.8)	0.010
RDS	51 (40.8)	36 (72.0)	<0.001	68 (45.9)	19 (70.4)	0.020	73 (46.8)	14 (73.7)	0.027
BPD	31 (24.8)	29 (58.0)	<0.001	41 (27.7)	19 (70.4)	<0.001	43 (27.6)	17 (89.5)	<0.001
IVH, grade ≥2	7 (5.6)	4 (8.0)	0.515	8 (5.4)	3 (11.1)	0.380	8 (5.2)	3 (15.8)	0.104
PVL	11 (8.9)	5 (10.0)	0.779	15 (10.2)	1 (3.7)	0.472	15 (9.7)	1 (5.3)	1.000
NEC	8 (6.4)	8 (16.0)	0.047	10 (6.8)	6 (22.2)	0.010	11 (7.1)	5 (26.3)	0.018

^*Significant findings (P < 0.05) are presented in bold.

Values are mean ± standard deviation or number (%). GA, gestational age; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia.