Table 2. Table summarizing the effects vitamin E on biochemical and histological markers of NAFLD.

NAFLD, nonalcoholic fatty liver disease; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transferase

[13-20]

Author and year	Improvement in liver function tests (ALT, AST, ALP, GGT)	Improvement in NAFLD Activity Score (NAS)	Improvement in steatosis	Improvement in fibrosis score	Improvement in ballooning	Improvement in lobular inflammation
Sanyal et al. 2010	Significant reduction in mean AST, ALT, ALP, and GGT levels	Yes	Yes	No	Yes	Yes
Foster et al. 2011	No	Not recorded	Yes	Not recorded	Not recorded	Not recorded
Hoofnagle et al. 2013	Significant reduction in ALT only	No	Yes	No	Yes	Yes
Aller et al. 2015	Significant reduction in GGT only	Not recorded	Not recorded	Yes	Not recorded	Not recorded
Polyzos et al. 2017	No	Not recorded	No	No	Not recorded	Not recorded
Pervez et al. 2018	Significant reduction in mean AST and ALT in the treatment group	Not recorded	No	Not recorded	Not recorded	Yes
Bril et al. 2019	Significant reduction in mean AST and ALT in both treatment groups	Not recorded	Yes	No	No	No
Anushiravani et al. 2019	Significant reduction in mean AST and ALT in treatment groups	Not recorded	Not recorded	Not recorded	Not recorded	Not recorded
No. of results showing improvement	6	1	4	1	2	3
No. of results showing no improvement	2	1	2	4	1	1
No. of results not recorded	0	6	2	3	5	4