Table 3 –
Biopsy characteristics
| Author | TBx | SBx | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Navigation | Route | Concurrent SBx | Total no. of cores | No. of lesions per patient | No. of cores per lesion |
Operators | Route | No. of cores | ||
| No. | Experience | |||||||||
| Baco et al [17] | MRI/TRUS fusion | TR | Yes | Median (range): 2 (1–4) | ≤2 | ≤2 | 1 | No. of previous biopsies: >200 | TR | 12a |
| Bello et al [18] | NR | NR | Yes | NR | NR | NR | NR | NR | TR | NR (“standard”) |
| Kasivisvanathan et al [11] | Cognitive (33), MRI/TRUS fusion (219) | TR (227), TP (25) | No | Median (range): 4 (3–7) | Median (range): 1 (1–3) | ≤4 | 33 | No. of previous biopsies: 100 (IQR 28–250) | TR | Median (range): 12 (12–12) |
| Panebianco et al [19] | Cognitive | TR | Yes | 2 | 1 | 2 | 2 | >3 yr | TR | 14 |
| Park et al [20] | Cognitive | TR | Yes | Mean (range): 0.84 (0–3) | NR | 0–3 | 1 | >2 yr | TR | Mean (range): 11.1 (10–14)b |
| Porpiglia et al [21] | MRI/TRUS fusion | TR (55), TP (26) | Noc | Mean: 6.0 | 1 (54 pts), 2 (27 pts) | NR 3–6 |
2 | >1 yr | TR | Median (range): 12 (12–12) |
| Sciarra et al [22] | Cognitive | TR | Yes | 0–6 | 0–3 | 2 | 1 | Experienced | TR | 10 |
| Taverna et al [23] | Cognitive | TR | Yes | NR | No limit | 4 | 1 | NR | TR | 13 |
| Tonttila et al [24] | Cognitive | TR | Yes | 2.0 | 1 (26 pts), 2 (14 pts) | 1.8 (1st lesion), 1.1 (2nd lesion) | 3 | None | TR | Median (range): 12 (10–12) |
DRE = digital rectal examination; IQR = interquartile range; MRI = magnetic resonance imaging; NR = not reported; pts = patients; SBx = systematic TRUS-guided biopsy; TBx = targeted biopsy; TP = transperineal; TR = transrectal; TRUS = transrectal ultrasound.
a
Plus up to two cores for DRE or TRUS suspicious lesions.
b
Including up to two cores for hypoechoic lesions on TRUS.
c
Only SBx was performed in MRI-negative patients.