TABLE VIII.
Comparison of Hemoglobin and Hematocrit Levels Between IV and Topical TXA Groups
| IV TXA Group | Topical TXA Group | Difference in Means (95% CI)* | P Value | |||
| No. | Mean ± SD | No. | Mean ± SD | |||
| Hemoglobin (g/dL) | ||||||
| Preop. | 31 | 13.53 ± 1.13 | 32 | 13.75 ± 1.13 | ||
| 1 hr after tourniquet release (PACU) | 31 | 11.29 ± 1.21 | 32 | 11.41 ± 1.02 | 0.05 (−0.25, 0.35) | 0.741 |
| POD1 | 30 | 11.12 ± 1.04 | 31 | 10.53 ± 0.13 | 0.72 (0.35, 1.10) | <0.001 |
| POD2 | 30 | 10.28 ± 1.19 | 32 | 9.94 ± 1.03 | 0.53 (0.16, 0 .90) | 0.005 |
| Hematocrit (%) | ||||||
| Preop. | 31 | 40.8 ± 3.2 | 32 | 41 ± 2.8 | ||
| 1 hr after tourniquet release (PACU) | 31 | 33.6 ± 3.6 | 32 | 33.8 ± 2.6 | −0.01 (−1, 0.8) | 0.847 |
| POD1 | 30 | 35.6 ± 12 | 31 | 31.5 ± 4 | 4.2 (−0.1, 8.5) | 0.058 |
| POD2 | 30 | 31 ± 3.5 | 32 | 29.8 ± 2.7 | 1.4 (0.4, 2.5) | 0.006 |
*
Comparisons adjusted for baseline systemic hemoglobin and hematocrit blood levels.