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. 2020 Jan 8;35(2):239–246. doi: 10.46497/ArchRheumatol.2020.7583

Table 1. Demographic and clinical features of patients with systemic lupus erythematosus.

Characteristics Non-ILD group (n=449) ILD group (n=56)    
  n % n % χ2 p
Age (year)         13.553 0.001
≤44 319 71.0 28 50    
45-59 101 22.5 18 32.1    
≥60 29 6.5 10 17.9    
Sex            
Female 392 87.3 49 87.5 0.002 0.967
Body mass index (kg/m2)     5.348 0.069  
<18.5 77 17.1 6 10.7    
18.5-23.9 315 70.2 37 66.1    
≥24 57 12.7 13 23.2    
SLE duration (year)       14.746 0.001
<1 250 55.7 16 28.6    
1-10 167 37.2 33 58.9    
≥10 32 7.1 7 12.5    
Dry cough 100 22.3 18 32.1 2.709 0.1
Moist rales 40 8.9 11 19.6 6.319 0.012
Malar rash 164 36.5 20 35.7 0.014 0.905
Epilepsy 8 1.8 0 0.0 1.014 0.314
Fever 160 35.6 20 35.7 0 0.991
Arthritis 221 49.2 33 58.9 1.877 0.171
Photosensitivity 58 12.9 6 10.7 0.218 0.64
Serositis 112 24.9 10 17.9 1.365 0.243
Neuropsychological involvement 40 8.9 1 1.8 3.386 0.066
Myalgia/myasthenia 11 2.4 2 3.6 0.25 0.617
Xerostomia/xeroma 37 8.2 4 7.1 0.08 0.777
Oral ulcer 41 9.1 6 10.7 0.148 0.701
Raynaud’s phenomenon 49 10.9 19 33.9 22.635 <0.001
Alopecia 60 13.4 9 16.1 0.31 0.578
Livedo reticularis 4 0.9 0 0.0 0.503 0.478
Finger tip vasculitis 17 3.8 3 5.4 0.323 0.57
Peripheral neuritis 7 1.6 0 0.0 0.885 0.347
Malar rash 120 26.7 11 19.6 1.3 0.254
Tachypnea 50 11.1 17 30.4 15.986 <0.001
SLEDAI         5.579 0.134
0-4 140 90.3 15 9.7    
5-9 156 85.2 27 14.8    
10-14 91 89.2 11 10.8    
≥15 62 95.4 3 4.6    
SDI         4.845 0.183
0 267 90.8 27 9.2    
1 118 86.8 18 3.2    
2 31 91.2 3 8.8    
≥3 33 80.5 8 19.5    
Abnormal electrocardiogram 244 54.3 34 60.7 0.817 0.366
ILD: Interstitial lung disease; SLE: Systemic lupus erythematosus; SLEDAI: Systemic lupus erythematosus disease activity index; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.