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. 2020 Jan 8;35(2):239–246. doi: 10.46497/ArchRheumatol.2020.7583

Table 2. Laboratory findings of patients with systemic lupus erythematosus.

Characteristics Non-ILD group (n=449) ILD group (n=56)    
  n % Mean±SD Quartile n % Mean±SD Quartile χ2 p
Leukopenia 171 38.1     22 39.3     0.03 0.86
Anemia 275 61.2     32 57.1     0.352 0.55
Thrombocytopenia 117 26.1     9 16.1     2.652 0.1
Urine protein 282 62.8     30 53.6     1.798 0.18
Urine RBC 172 38.3     18 32.1     0.806 0.37
Albumin (g/L)     25.5±36.1 30.97     28.5±36.8 32.35   0.26
Globulin (g/L)     29.4±38.8 34.64     31.1±39.2 35.93   0.24
Creatinine (μmol/L)   45.0±71.0 72.72     49.0±71.0 60.85   0.97
LDH (IU/L)     164.0±273.0 265.37     175.8±272.0 265.21   0.61
ESR (mm/h)     26.0±61.5 50.90     31.0±70.3 52.48   0.61
Abnormal CRP 210 46.8     28 50.0     0.208 0.65
IgG (g/L)     12.7±20.5 17.50     14.1±20.3 18.38   0.82
IgM (g/L)     1.2±1.4 1.21     0.8±1.3 1.15   0.62
IgA (g/L)     1.8±3.2 2.59     1.9±3.4 2.88   0.23
C3 (g/L)     0.3±0.7 0.53     0.4±0.9 0.64   0.03
C4 (g/L)     0.1±0.2 0.11     0.1±0.2 0.13   0.2
Rheumatoid factor 172 38.3     25 44.6     0.84 0.36
Anti-dsDNA (IU/mL)   4.4±32.0 22,10     2.0±24.0 16,79   0,02
Anti-cardiolipin IgM 37 8.2     2 3.6     1.523 0.22
Anti-cardiolipin IgG 90 20.0     15 26.8     1.374 0.24
Anti- 2GP1 86 19.2     6 10.7     2.38 0.12
Anti-ANCA 21 4.7     5 8.9     1.843 0.18
Anti-U1RNP 222 49.4     35 62.5     3.396 0.07
Anti-SM 150 33.4     23 41.1     1.298 0.25
Anti-SSA 294 65.5     32 57.1     1.512 0.22
Anti-SSB 114 25.4     12 21.4     0.417 0.52
Anti-SCL-70 6 1.3     0 0.0     0.757 0.38
Anti-PM-SCL 17 3.8     1 1.8     0.58 0.45
Anti-JO-1 3 0.7     0 0.0     0.376 0.54
Anti-centromere 11 2.4     3 5.4     1.561 0.21
Anti-PCNA 6 1.3     0 0.0     0.757 0.38
Anti-nucleosome 228 50.8     22 39.3     2.631 0.11
Anti-histone 164 6.5     17 30.4     0.824 0.36
Anti-rRNP 189 42.1     21 37.5     0.432 0.51
Anti-mitochondrial 65 14.5     7 12.5     0.159 0.69
ILD: Interstitial lung disease; SD: Standard deviation; RBC: Red blood cell; LDH: Lactate dehydrogenase; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; Ig: Immunoglobulin; C: Complement; dsDNA: Double-stranded deoxyribonucleic acid; 2GP1: beta-2 glycoprotein 1; ANCA: Antineutrophil cytoplasmic antibodies; U1RNP: U1 ribonucleoprotein; SM: Smith; SSA/SSB: Anti-Ro/anti-La; Anti-SCL-70: Anti-topoisomerase I; PM/SCL: Polymyositis-scleroderma; JO-1: Histidyl-tRNA synthetase; PCNA: Proliferating cell nuclear antigen; RNP: Ribonucleoprotein.