Table 2. Laboratory findings of patients with systemic lupus erythematosus.
Characteristics | Non-ILD group (n=449) | ILD group (n=56) | ||||||||
n | % | Mean±SD | Quartile | n | % | Mean±SD | Quartile | χ2 | p | |
Leukopenia | 171 | 38.1 | 22 | 39.3 | 0.03 | 0.86 | ||||
Anemia | 275 | 61.2 | 32 | 57.1 | 0.352 | 0.55 | ||||
Thrombocytopenia | 117 | 26.1 | 9 | 16.1 | 2.652 | 0.1 | ||||
Urine protein | 282 | 62.8 | 30 | 53.6 | 1.798 | 0.18 | ||||
Urine RBC | 172 | 38.3 | 18 | 32.1 | 0.806 | 0.37 | ||||
Albumin (g/L) | 25.5±36.1 | 30.97 | 28.5±36.8 | 32.35 | 0.26 | |||||
Globulin (g/L) | 29.4±38.8 | 34.64 | 31.1±39.2 | 35.93 | 0.24 | |||||
Creatinine (μmol/L) | 45.0±71.0 | 72.72 | 49.0±71.0 | 60.85 | 0.97 | |||||
LDH (IU/L) | 164.0±273.0 | 265.37 | 175.8±272.0 | 265.21 | 0.61 | |||||
ESR (mm/h) | 26.0±61.5 | 50.90 | 31.0±70.3 | 52.48 | 0.61 | |||||
Abnormal CRP | 210 | 46.8 | 28 | 50.0 | 0.208 | 0.65 | ||||
IgG (g/L) | 12.7±20.5 | 17.50 | 14.1±20.3 | 18.38 | 0.82 | |||||
IgM (g/L) | 1.2±1.4 | 1.21 | 0.8±1.3 | 1.15 | 0.62 | |||||
IgA (g/L) | 1.8±3.2 | 2.59 | 1.9±3.4 | 2.88 | 0.23 | |||||
C3 (g/L) | 0.3±0.7 | 0.53 | 0.4±0.9 | 0.64 | 0.03 | |||||
C4 (g/L) | 0.1±0.2 | 0.11 | 0.1±0.2 | 0.13 | 0.2 | |||||
Rheumatoid factor | 172 | 38.3 | 25 | 44.6 | 0.84 | 0.36 | ||||
Anti-dsDNA (IU/mL) | 4.4±32.0 | 22,10 | 2.0±24.0 | 16,79 | 0,02 | |||||
Anti-cardiolipin IgM | 37 | 8.2 | 2 | 3.6 | 1.523 | 0.22 | ||||
Anti-cardiolipin IgG | 90 | 20.0 | 15 | 26.8 | 1.374 | 0.24 | ||||
Anti- 2GP1 | 86 | 19.2 | 6 | 10.7 | 2.38 | 0.12 | ||||
Anti-ANCA | 21 | 4.7 | 5 | 8.9 | 1.843 | 0.18 | ||||
Anti-U1RNP | 222 | 49.4 | 35 | 62.5 | 3.396 | 0.07 | ||||
Anti-SM | 150 | 33.4 | 23 | 41.1 | 1.298 | 0.25 | ||||
Anti-SSA | 294 | 65.5 | 32 | 57.1 | 1.512 | 0.22 | ||||
Anti-SSB | 114 | 25.4 | 12 | 21.4 | 0.417 | 0.52 | ||||
Anti-SCL-70 | 6 | 1.3 | 0 | 0.0 | 0.757 | 0.38 | ||||
Anti-PM-SCL | 17 | 3.8 | 1 | 1.8 | 0.58 | 0.45 | ||||
Anti-JO-1 | 3 | 0.7 | 0 | 0.0 | 0.376 | 0.54 | ||||
Anti-centromere | 11 | 2.4 | 3 | 5.4 | 1.561 | 0.21 | ||||
Anti-PCNA | 6 | 1.3 | 0 | 0.0 | 0.757 | 0.38 | ||||
Anti-nucleosome | 228 | 50.8 | 22 | 39.3 | 2.631 | 0.11 | ||||
Anti-histone | 164 | 6.5 | 17 | 30.4 | 0.824 | 0.36 | ||||
Anti-rRNP | 189 | 42.1 | 21 | 37.5 | 0.432 | 0.51 | ||||
Anti-mitochondrial | 65 | 14.5 | 7 | 12.5 | 0.159 | 0.69 | ||||
ILD: Interstitial lung disease; SD: Standard deviation; RBC: Red blood cell; LDH: Lactate dehydrogenase; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; Ig: Immunoglobulin; C: Complement; dsDNA: Double-stranded deoxyribonucleic acid; 2GP1: beta-2 glycoprotein 1; ANCA: Antineutrophil cytoplasmic antibodies; U1RNP: U1 ribonucleoprotein; SM: Smith; SSA/SSB: Anti-Ro/anti-La; Anti-SCL-70: Anti-topoisomerase I; PM/SCL: Polymyositis-scleroderma; JO-1: Histidyl-tRNA synthetase; PCNA: Proliferating cell nuclear antigen; RNP: Ribonucleoprotein. |