Table 1.
Name | Function* | Inhibitor/s |
---|---|---|
PARG | dePARylation deMARylation, deMARylation from DNA, | Salicylanilides[104] |
RBPI-3 [103] | ||
Gallotannin[122] | ||
PDD00017273[108] | ||
TARG1 | dePARylation, OAADPr hydrolysis, deMARylation from DNA, | No |
MacroD1 | deMARylation from Asp and Glu, OAADPr hydrolysis | No |
MacroD2 | deMARylation from Asp and Glu, OAADPr hydrolysis, deMARylation from DNA, | No |
ARH1 | deMARylation from Arg | No |
ARH3 | dePARylation, deMARylation, deMARylation from Ser, deMARylation from DNA, | No |
ENPP1 | deMARylation from DNA, phosphatase, | No |
NUDT16 | Phosphatase, release PAR from proteins | No |
NUDT5 | Phosphatase-acts on free OADPr | TH5427119 |
See text for details