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. Author manuscript; available in PMC: 2020 Aug 5.
Published in final edited form as: DNA Repair (Amst). 2019 Feb 8;76:20–29. doi: 10.1016/j.dnarep.2019.02.002

Table 1.

ADPribosylation degrading proteins, functions and inhibitors

Name Function* Inhibitor/s
PARG dePARylation deMARylation, deMARylation from DNA, Salicylanilides[104]
RBPI-3 [103]
Gallotannin[122]
PDD00017273[108]
TARG1 dePARylation, OAADPr hydrolysis, deMARylation from DNA, No
MacroD1 deMARylation from Asp and Glu, OAADPr hydrolysis No
MacroD2 deMARylation from Asp and Glu, OAADPr hydrolysis, deMARylation from DNA, No
ARH1 deMARylation from Arg No
ARH3 dePARylation, deMARylation, deMARylation from Ser, deMARylation from DNA, No
ENPP1 deMARylation from DNA, phosphatase, No
NUDT16 Phosphatase, release PAR from proteins No
NUDT5 Phosphatase-acts on free OADPr TH5427119
*

See text for details