Table 2.
Clinical Factors Independently Associated With QTc Prolongation ≥500 ms
Univariate Analysis |
Multivariate Analysis |
|||||
---|---|---|---|---|---|---|
OR | 95% CI | p Value | OR | 95% CI | p Value | |
Age >65 yrs | 2.82 | 1.67–4.75 | <0.001 | 3.00 | 1.62–5.54 | <0.001 |
History of congestive heart failure | 3.74 | 1.75–8.01 | 0.001 | 4.65 | 2.01–10.74 | <0.001 |
Body mass index ≥30 kg/m2 | 0.48 | 0.30–0.78 | 0.003 | 0.45 | 0.26–0.78 | 0.005 |
Peak troponin >0.04 mg/ml | 3.10 | 1.85–5.19 | <0.001 | 3.89 | 2.22–6.83 | <0.001 |
Admission creatinine ≥1.5 mg/dl | 2.42 | 1.45–4.06 | <0.001 | 2.22 | 1.28–3.84 | 0.005 |
Concomitant use of drugs with known risk of torsade de pointes | 1.73 | 1.04–2.90 | 0.036 | 1.51 | 0.86–2.66 | 0.154 |
SI units for creatinine (μmol/l) = mg/dl × 88.4.
SI units for troponin I (μg/l) = ng/ml × 1.
CI = confidence interval; OR = odds ratio; other abbreviation as in Table 1.