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. 2020 Jul 9;5(13):e136857. doi: 10.1172/jci.insight.136857

Figure 1. TSC1 deletion in NPCs is associated with mTOR pathway activation in PTCs.

Figure 1

Kidney sections at different embryonic ages as indicated were stained with (A) H&E. (B) Enlarged kidney sections as in A. (C) Phosphorylated S6 analyzed by IF. (D) LTL antibody by IHC. Scale bar: 50 μm. n = 3. Black arrows indicate the injured PTCs with swollen appearance and occluded lumen. TSC, tuberous sclerosis complex; NPCs, nephron progenitor cells; PTCs, proximal tubular cells; IF, immunofluorescent; LTL lotus tetragonolobus lectin.