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. 2020 Jul 9;5(13):e138295. doi: 10.1172/jci.insight.138295

Figure 2. Effect of scleraxis deletion on tendon growth.

Figure 2

(A) Representative Fast Green–stained cross-section histology from Scx+ and ScxΔ mice at either 7D or 14D after synergist ablation/plantaris growth procedure, demonstrating general morphology and cell density. The original tendon (OT) and neotendon (NT) are indicated by the hashed line. Scale bar: 200 μm. (B and C) Quantification of original tendon, neotendon, and total tendon cross-sectional area (CSA) (B) and cell density (C). Values are mean ± SD. Differences between groups were tested using a 2-way ANOVA; a, significantly different (P < 0.05) from 7D Scx+; b, significantly different (P < 0.05) from 7D ScxΔ; c, significantly different (P < 0.05) from 14D Scx+. N ≥ 3 mice per group.