Skip to main content
. 2020 Aug 5;6(32):eaba8415. doi: 10.1126/sciadv.aba8415

Fig. 6. Human PanNET RNA-seq data support dysregulation of ERVs and protein-coding genes.

Fig. 6

(A) Schematic representation of human PanNET RNA-seq analysis. (B) Volcano plot highlighting the top 1000 DEGs in DAXX mutant human PanNETs, with four genes reaching statistical significance. Red indicates up-regulated genes and blue indicates down-regulated genes. (C) Schematic representation of the genomic locus containing the significantly up-regulated genes, SERINC2 and FABP3, and adjacent ERV, HERVIP10F-int (indicated in brown) with LTRs 10A and 10E (indicated in yellow).