Table 1. Clinical characteristics and plasma legumain levels.

	CAD (−)	P value	CAD	Complex lesion (−)	Complex lesion	Complex lesion (+)
	(n = 147)	CAD (−) vs. CAD	(n = 225)	(n = 185)	(+) vs. (−)	(n = 40)
Age (years)	66 ± 10	< 0.001	69 ± 10	69 ± 10	0.49	68 ± 10
Gender (male)	88 (60%)	< 0.001	174 (77%)	142 (77%)	0.90	32 (80%)
Hypertension	89 (61%)	< 0.001	176 (78%)	148 (80%)	0.30	28 (70%)
SBP (mmHg)	130 ± 21	0.20	133 ± 20	133 ± 21	0.76	132 ± 19
Diabetes mellitus	22 (15%)	< 0.001	83 (37%)	70 (38%)	0.80	13 (33%)
Smoking	46 (31%)	0.10	92 (41%)	78 (42%)	0.80	14 (35%)
Hyperlipidemia	67 (46%)	< 0.025	132 (59%)	109 (59%)	0.98	23 (58%)
Statin	45 (31%)	< 0.01	101 (45%)	88 (48%)	0.20	13 (33%)
LDL-C (mg/dL)	113 ± 28	0.72	114 ± 32	111 ± 32	< 0.005	127 ± 28
HDL-C (mg/dL)	60 ± 14	< 0.001	51 ± 13	51 ± 14	0.99	51 ± 13
hsCRP levels	0.46	< 0.001	0.60	0.60	0.93	0.60
(mg/L)	[0.22, 0.89]		[0.32, 1.53]	[0.32, 1.51]		[0.34, 1.53]
> 1.0mg/L	33 (22%)	< 0.025	78 (35%)	65 (35%)	0.90	13 (33%)
Legumain levels	4.99	0.81	5.08	4.93	< 0.01	6.05
(ng/mL)	[3.84, 6.88]		[3.87, 6.82]	[3.76, 6.52]		[4.64, 8.64]
> 5.5 ng/mL	58 (39%)	0.90	92 (41%)	68 (37%)	< 0.025	24 (60%)

Data are presented as the mean ± SD or the number (%) of patients, except for hsCRP and legumain levels, which are presented as the median value and interquartile range.

SBP indicates systolic blood pressure; LDL-C, LDL-cholesterol; and HDL-C, HDL-cholesterol.