Table 3. Comparison of the accuracy of risk assessment for the development of coronary heart disease between the models adjusted for potential risk factors with and without small dense low-density lipoprotein cholesterol or low-density lipoprotein cholesterol.

	c-statistics (95% CI)	p value for difference in c-statistics	cNRI (95% CI) after adding sdLDL cholesterol or LDL cholesterol	p value for NRI	IDI (95% CI) after adding sdLDL cholesterol or LDL cholesterol	p value for IDI
Basic model	0.774 (0.730–0.817)	reference	-	reference	-	reference
Basic model + log(serum sdLDL cholesterol)	0.794 (0.754–0.835)	0.02	0.40 (0.18–0.62)	< 0.001	0.008 (0.001–0.01)	0.02
Basic model + serum LDL cholesterol	0.793 (0.750–0.836)	0.06	0.49 (0.27–0.70)	< 0.001	0.007 (0.002–0.01)	0.01

Abbreviations: CI, confidence interval; cNRI, continuous net reclassification improvement; IDI, integrated discrimination improvement; LDL, low-density lipoprotein; sdLDL, small dense low-density lipoprotein.

The basic model was adjusted for age, sex, systolic blood pressure, use of antihypertensive agents, hemoglobin A1c, use of glucose-lowering agents, high-density lipoprotein-cholesterol, lipid-modifying agents, body mass index, estimated glomerular filtration rate, electrocardiogram abnormalities, current smoking, current drinking, and regular exercise.