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. 2020 Jul 30;14:31. doi: 10.3389/fnana.2020.00031

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Copyright © 2020 O’Leary, Davoli, Belliveau, Tanti, Ma, Farmer, Turecki, Murai and Mechawar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VIM-IR astrocytes display diverse morphological features. (A) Two adjacent VIM-IR astrocyte cell somas (arrowheads) displaying a twin cell morphology were commonly observed in all human brain regions examined. (B) In the caudate nucleus, we observed long bundles of parallel VIM-IR fibers (arrowheads) of no immediately discernable cell origin or target, but which often received contacts from neighboring VIM-IR astrocytes. (C) Some VIM-IR astrocytes extended parallel projections (arrowheads) which may be the origin of the fiber bundles illustrated in (C) and which appear (black outline) from outside of the z-plane of the section, suggesting that VIM-IR astrocytes contact distal targets. Scale bars = 50 μm.