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Degranulation and granule secretion of B7-H3 CAR-NK-92MI cells. (A) Surface expression of CD107a, as measured by mean fluorescence intensity (MFI), detected in CAR-NK-92MI cells compared to NK-92MI cells in response to A549 or NCI-H23 cells. (B, C) Secretion of perforin and granzyme B from CAR-NK-92MI cells compared to NK-92MI cells using flow cytometric analysis. Data are presented as mean ± SEM of triplicate samples. **p < 0.01; *p < 0.05.
