Table II.
Association between SCGB2A1 expression and clinicopathological variables.
| Characteristics (group A vs. group B) | OR of SCGB2A1 expression (95% CI) | Median (P25,P75) of SCGB2A1 expression (group A) | Median (P25,P75) of S CGB2A1 expression (group B) | P-value |
|---|---|---|---|---|
| Age at diagnosis, >64 vs. <64 years | 0.41 (0.29-0.58) | 561 (122,1696) | 207 (40,799) | <0.001 |
| Ethnicity, African American vs. Caucasian | 0.87 (0.64-1.16) | 174 (36,1334) | 388 (77,1289) | 0.344 |
| Menopause status, post vs. pre | 0.89 (0.54-1.44) | 296 (55,1088) | 926 (263,2069) | 0.622 |
| Surgical approach, open vs. minimally invasive | 0.98 (0.68-1.40) | 334 (62,1169) | 374 (61,1355) | 0.899 |
| Histological type, endometrioid vs. serous | 4.00 (2.60-6.33) | 555 (142,1710) | 48 (13,141) | <0.001 |
| Grade, high vs. low/moderate | 0.11 (0.07-0.17) | 113 (26,420) | 1,166 (415,2264) | <0.001 |
| Tumor invasion depth, ≥50 vs. <50% | 0.73 (0.50-1.05) | 297 (34,1186) | 491 (100,1517) | 0.090 |
| Tumor status, with vs. tumor free | 0.28 (0.15-0.48) | 81 (16,380) | 448 (102,1466) | <0.001 |
| Residual tumor, R1/R2 vs. R0 | 0.49 (0.24-0.97) | 82 (15,549) | 350 (68,1355) | 0.046 |
| Peritoneal washing, positive vs. negative | 0.41 (0.22-0.75) | 99 (26,544) | 388 (68,1335) | 0.004 |
| Pelvic lymph node metastasis, yes vs. no | 0.27 (0.15-0.47) | 89 (11,349) | 426 (82,1467) | <0.001 |
| Para-aortic lymph node metastasis, yes vs. no | 0.42 (0.19-0.87) | 141 (8,411) | 362 (66,1205) | 0.024 |
| Stage, II vs. I | 0.59 (0.49-0.71) | 373 (78,782) | 484 (104,1654) | <0.001 |
OR, odds ratio; CI, confidence interval; SCGB2A1, secretoglobin family 2A member1