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. 2020 Jul 30;11:1170. doi: 10.3389/fphar.2020.01170

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Copyright © 2020 Ye, Lu, Wang, Ge, Liu, Qi, Fu, Zhang, Zhang, Sun and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hydroxysafflor yellow A (HSYA) alleviates I/R induced cardiac impairment. (A, B) The representative images and analysis results of triphenyl tetrazolium chloride (TTC) staining (n=4 per group). (C–E) Effects of HSYA on serum creatine kinase-MB (CK-MB), aspartate transaminase (AST), and lactic dehydrogenase (LDH) levels in the rats subjected to ischemia/reperfusion (I/R) injury (n=10 per group). (F) The representative images of H&E staining (Scale bar, 200 μm, n=4 per group). Data are presented as means ± SEM. ^###P < 0.001 vs. the sham group, *P < 0.05, **P < 0.01 vs. the I/R group.