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. 2020 Jul 30;11:1170. doi: 10.3389/fphar.2020.01170

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Copyright © 2020 Ye, Lu, Wang, Ge, Liu, Qi, Fu, Zhang, Zhang, Sun and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hydroxysafflor yellow A (HSYA) inhibits the secretion of inflammatory factors. (A) Serum TNF-α level was analyzed by ELISA 24 h post-reperfusion (n=6 per group). (B) Serum interleukin (IL)-1β level was analyzed by ELISA 24 h post-reperfusion (n=6 per group). (C) Serum IL-18 level was analyzed by ELISA 24 h post-reperfusion (n=6 per group). Data are presented as means ± SEM. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. the sham group, *P <0.05, **P < 0.01, ***P < 0.001 vs. the ischemia/reperfusion (I/R) group.