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. 2020 Aug 4;58:102932. doi: 10.1016/j.ebiom.2020.102932

Table 3.

Metabolic profile score Tpred association with mean dietary intake adjusted for age, gender, smoking, alcohol consumption, BMI and study centre, the IMI DIRECT cohorts.

Cohort I n=403
Cohort II n=458
β a 95% CI P value β a 95% CI P value
Fibre (NSP) per
1000 kcal
0.34 −0.07, 0.74 0.09 0.45 0.04, 0.85 0.03
Fruit/vegetables per
1000 kcal
11.85 −7.05, 30.75 0.22 23.22 5.11, 41.33 0.01
Wholegrains per
1000 kcal
3.36 0.31, 6.40 0.03 2.82 0.06, 5.57 0.04
Fish per
1000 kcal
9.17 3.98, 14.36 0.0006 12.17 7.23, 17.11 <0.0001
Carbohydrate
%TEI
−0.65 −1.89, 0.58 0.31 −1.27 −2.47, −0.07 0.04
Protein
%TEI
0.66 1.30, 0.02 0.04 1.51 0.87, 2.17 <0.0001
Fat
%TEI
−0.11 −1.26, 1.05 0.86 −0.69 −1.77, 0.39 0.21
Saturated fat
%TEI
−0.92 −1.56, −0.28 0.005 −0.98 −1.53, −0.42 0.0006
Added sugar
%TEI
−0.39 −1.2, 0.42 0.35 −1.21 −1.98, −0.43 0.002
Mean kcal −73.53 −144.71, −2.35 0.04 −122.51 −186.56, −38.46 0.003
HDI score 0.24 −0.07, 0.55 0.09 0.45 0.12, 0.76 0.006

Abbreviation: Cohort 1; participants with normal or impaired glucose regulation, cohort 2; participants with Diabetes type 2, NSP, non‐starch polysaccharides,%TEI, percentage of total energy intake, 95% CI, confidential interval, HDI, Healthy Diet Indicator. a, Generalised linear regression model coefficient represents the mean change in the nutritional variable for one unit change (increase) in Tpred score fully adjusted models.