FIG 2.

Magnitudes of plasma Env-specific IgA binding responses by ELISA, plasma ADCC antibody titer, and plasma and breast milk ADCC potency in transmitting and nontransmitting women. The magnitude of plasma total IgA (A) binding to B.con gp140, measured as the area under the curve by ELISA, was higher in transmitting than in nontransmitting women (median log₁₀ AUC, 0.01 versus 0.48). Plasma ADCC Ab titer (B) was also higher in transmitting women than in nontransmitting women (median log₁₀ ADCC Ab titer, 2.29 versus 2.09). Plasma (C) and breast milk (D) ADCC potencies, as maximum percent specific killing, were higher in transmitting than in nontransmitting women (median max percent specific killing, 26.06 versus 25.00, and 27.66 versus 25.86). Medians are represented by horizontal black lines. The box represents the interquartile range, and the dashed lines extend to the highest and lowest values.